About the Authors

Hanna Nilsson

Affiliation Department of Cardiothoracic and Vascular Surgery & Institute of Clinical Medicine, Aarhus University Hospital, Aarhus, Denmark

Erik Lerkevang Grove

Affiliation Department of Cardiology, Aarhus University Hospital, Aarhus, Denmark

Torben Bjerregaard Larsen

Affiliations Department of Cardiology, Centre for Cardiovascular Research, Aalborg University Hospital, Aalborg, Denmark, Aalborg Thrombosis Research Unit, Department of Clinical Medicine, The Faculty of Medicine, Aalborg University, Aalborg, Denmark

Peter Brønnum Nielsen

Affiliation Aalborg Thrombosis Research Unit, Department of Clinical Medicine, The Faculty of Medicine, Aalborg University, Aalborg, Denmark

Flemming Skjøth

Affiliation Aalborg Thrombosis Research Unit, Department of Clinical Medicine, The Faculty of Medicine, Aalborg University, Aalborg, Denmark

Marianne Maegaard

Affiliation Department of Cardiothoracic and Vascular Surgery & Institute of Clinical Medicine, Aarhus University Hospital, Aarhus, Denmark

Thomas Decker Christensen

tdc@ki.au.dk

Affiliation Department of Cardiothoracic and Vascular Surgery & Institute of Clinical Medicine, Aarhus University Hospital, Aarhus, Denmark

Competing Interests

Erik Lerkevang Grove has received speaker honoraria from AstraZeneca, Baxter, Bayer, Boehringer Ingelheim, Pfizer and Sysmex and serves on advisory boards for AstraZeneca, Bayer, and Bristol-Myers Squibb. Torben Bjerregaard Larsen has served as an investigator for Janssen Scientific Affairs, LLC and Boehringer Ingelheim and has been on the speaker bureaus for Bayer, BMS/Pfizer, Roche Diagnostics, Takeda and Boehringer Ingelheim. Other authors ? none declared. Thomas Decker Christensen has been on the speaker bureaus for AstraZeneca, Boehringer Ingelheim, Pfizer, Takeda and Bristol-Myers Squibb, and has been a member of an advisory board in Bristol-Myers Squibb. No other relationships are present. The project was funded by a non-restricted grant from Takeda, Denmark, and this does not alter the authors' adherence to PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: HN ELG TBL PBN FS TDC. Performed the experiments: HN ELG TBL PBN FS MM TDC. Analyzed the data: HN ELG TBL PBN FS TDC. Contributed reagents/materials/analysis tools: HN ELG TBL PBN FS MM TDC. Wrote the paper: HN ELG TBL PBN FS MM TDC.