About the Authors

Dorit Samocha-Bonet

d.samochabonet@garvan.org.au

Affiliations Diabetes and Metabolism Division, Garvan Institute of Medical Research, Sydney, Australia, Faculty of Medicine, UNSW (The University of New South Wales), Sydney, Australia

Donald J. Chisholm

Affiliations Diabetes and Metabolism Division, Garvan Institute of Medical Research, Sydney, Australia, Faculty of Medicine, UNSW (The University of New South Wales), Sydney, Australia

Fiona M. Gribble

Affiliation Cambridge Institute of Medical Research and Department of Clinical Biochemistry, University of Cambridge, Cambridge, United Kingdom

Adelle C. F. Coster

Affiliation School of Mathematics and Statistics, UNSW (The University of New South Wales), Sydney, Australia

Kevin H. Carpenter

Affiliation Disciplines of Genetic Medicine & Paediatrics and Child Health, University of Sydney, Sydney, Australia

Graham R. D. Jones

Affiliations Faculty of Medicine, UNSW (The University of New South Wales), Sydney, Australia, Department of Chemical Pathology, St. Vincent's Hospital, Sydney, Australia

Jens J. Holst

Affiliation NNF Center for Basic Metabolic Research, Department of Biomedical Sciences, University of Copenhagen, Panum Institute, Copenhagen, Denmark

Jerry R. Greenfield

Affiliations Diabetes and Metabolism Division, Garvan Institute of Medical Research, Sydney, Australia, Faculty of Medicine, UNSW (The University of New South Wales), Sydney, Australia, Department of Endocrinology and Diabetes Center, St. Vincent's Hospital, Sydney, Australia

Competing Interests

Carpenter KH, Coster ACF, and Jones GRD have nothing to declare; Chisholm DJ has been a board member for Astra Zeneca/Bristol Myer Squibb (Member/Chairman of Australian and International Advisory Board) and has received speaker honoraria from Astra Zeneca/Bristol Myers Squibb and MSD; Gribble FM is a board member of BioKier, consultant for Roche, and has received speaker honoraria from Novo Nordisk and Merck, and travel/accommodation expenses from Merck. Holst JJ is a consultant to NovoNordisk and holds grants from Novartis and Merck. Greenfield JR was a Principal Investigator on an Investigator-Initiated Studies Program grant from Merck and Co., awarded to the Garvan Institute of Medical Research, and Samocha-Bonet D was partly supported by this grant. This does not alter the authors' adherence to PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: DS-B DJC JRG. Performed the experiments: DS-B JJH KHC GRDJ JRG. Analyzed the data: DS-B ACFC. Contributed reagents/materials/analysis tools: JJH KHC GRDJ. Wrote the paper: DS-B DJC JRG. Contributed to discussion: FMG JJH GRDJ.