About the Authors

Payel Das

daspa@us.ibm.com

Affiliation Computational Biology Center, IBM Thomas J. Watson Research Center, 1101 Kitchawan Road, Yorktown Heights, New York 10598, United States of America

Seung-gu Kang

Affiliation Computational Biology Center, IBM Thomas J. Watson Research Center, 1101 Kitchawan Road, Yorktown Heights, New York 10598, United States of America

Sally Temple

Affiliation Neural Stem Cell Institute, Rensselaer, New York 12144, United States of America

Georges Belfort

Affiliation Howard P. Isermann Department of Chemical and Biological Engineering and Center for Biotechnology and Interdisciplinary Studies, Rensselaer Polytechnic Institute, Troy, New York 12180, United States of America

Competing Interests

This work was supported by the IBM Blue Gene Science program. Co-authors Payel Das and Seung-gu Kang are affiliated with IBM Research. There are no patents, products in development or marketed products to declare. This does not alter the authors' adherence to all the PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: PD ST GB. Performed the experiments: PD SK. Analyzed the data: PD. Contributed reagents/materials/analysis tools: SK PD. Wrote the paper: PD SK ST GB.