About the Authors

Mark J. Hoser

markhoser@gmail.com

Affiliation Molecular Biology, GeneForm Technologies, Broadstairs, United Kingdom

Hannu K. Mansukoski

Affiliation Medical communication, Pfizer, Sandwhich, United Kingdom

Scott W. Morrical

Affiliation Department of Biochemistry, University of Vermont, Burlington, United States of America

Kevin E. Eboigbodin

Affiliation Research and Development, Orion Diagnostica, Espoo, Finland

Competing Interests

Orion Diagnostica Oy has a commercial interest in disclosure of the SIBA technology. Geneform Technologies, UK is owned by Orion Diagnostica Oy. Pfizer has no role with SIBA but rather is the current address for HKM. SIBA was invented by MJH and all patents/patent applications are owned by Orion Diagnostica Oy. MJH and KEE are employees of Geneform Technologies Ltd, UK and Orion Diagnostica Oy, Finland respectively. HKM is a previous employee of Geneform Technologies, UK who is now an employee of Pfizer, UK. This does not alter our adherence to PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: KEE MJH HKM. Performed the experiments: KEE HKM. Analyzed the data: KEE MJH HKM. Contributed reagents/materials/analysis tools: SWM. Wrote the paper: KEE MJH SWM. Contributed to recombinase production: SWM. Wrote the manuscript: MJH KEE. Reviewed the manuscript prior to submission: SWM.