About the Authors

Laila Elsherif

Affiliation Department of Biochemistry and Biophysics, The University of North Carolina at Chapel Hill, Chapel Hill, NC, United States of America

Mehmet Ozler

Affiliation Department of Biochemistry and Biophysics, The University of North Carolina at Chapel Hill, Chapel Hill, NC, United States of America

Mohamed A. Zayed

Affiliation Department of Biochemistry and Biophysics, The University of North Carolina at Chapel Hill, Chapel Hill, NC, United States of America

Jessica H. Shen

Affiliation Department of Biochemistry and Biophysics, The University of North Carolina at Chapel Hill, Chapel Hill, NC, United States of America

Jonathan Chernoff

Affiliation Cancer Biology Program, Fox Chase Cancer Center, Philadelphia, PA, United States of America

James E. Faber

Affiliations Department of Cell Biology and Physiology, The University of North Carolina at Chapel Hill, Chapel Hill, NC, United States of America, McAllister Heart Institute, The University of North Carolina at Chapel Hill, Chapel Hill, NC, United States of America

Leslie V. Parise

parise@med.unc.edu

Affiliations Department of Biochemistry and Biophysics, The University of North Carolina at Chapel Hill, Chapel Hill, NC, United States of America, McAllister Heart Institute, The University of North Carolina at Chapel Hill, Chapel Hill, NC, United States of America, Lineberger Comprehensive Cancer Center, The University of North Carolina at Chapel Hill, Chapel Hill, NC, United States of America

Competing Interests

The authors have read the journal's policy and have the following conflicts: LVP - Assoc Editor: Blood, Consultant: Bayer, BD, Biogen. This does not alter the authors' adherence to all the PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: LE LVP. Performed the experiments: LE MO MAZ JHS. Analyzed the data: LE. Contributed reagents/materials/analysis tools: JC JF. Wrote the paper: LVP LE.