About the Authors

John W. Newman

Affiliations USDA, ARS, WHNRC, Obesity and Metabolism Research Unit, Davis, CA, United States of America, Department of Nutrition, University of California Davis, Davis, CA, United States of America

Theresa L. Pedersen

Affiliation USDA, ARS, WHNRC, Obesity and Metabolism Research Unit, Davis, CA, United States of America

Verdayne R. Brandenburg

Affiliation Family Medicine, Sanford School of Medicine, University of South Dakota, Sioux Falls, SD, United States of America

William S. Harris

Affiliation Internal Medicine, Sanford School of Medicine, University of South Dakota, Sioux Falls, SD, United States of America

Gregory C. Shearer

gcs13@psu.edu

Affiliations Internal Medicine, Sanford School of Medicine, University of South Dakota, Sioux Falls, SD, United States of America, Basic Biomedical Sciences, Sanford School of Medicine, University of South Dakota, Sioux Falls, SD, United States of America, Cardiovascular Health Research Center, Sanford Research/USD, Sioux Falls, South Dakota, United States of America, Department of Nutritional Sciences, The Pennsylvania State University, University Park, Pennsylvania, United States of America

Competing Interests

JWN, TLP and VRB have nothing to disclose. This was an investigator-initiated study funded by GlaxoSmithKline. GlaxoSmithKline had no role in analysis or interpretation of the study results. GCS and WSH received speakership honoraria from GlaxoSmithKline while the trial was ongoing. This does not alter the authors' adherence to PLOS ONE policies on sharing data and materials; however, in order to protect participant privacy, data are not being made publicly available.

Author Contributions

Conceived and designed the experiments: GCS JWN. Performed the experiments: JWN TLP VRB WSH GCS. Analyzed the data: JWN TLP GCS. Contributed reagents/materials/analysis tools: JWN TLP GCS. Wrote the paper: GCS JWN.