About the Authors
- Vikash Pandey
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Affiliation Max Planck Institute for Molecular Genetics, Department Vertebrate Genomics, Berlin, Germany
- Marc Sultan
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Affiliation Max Planck Institute for Molecular Genetics, Department Vertebrate Genomics, Berlin, Germany
- Karl Kashofer
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Affiliation Institute of Pathology, Medical University of Graz, Graz, Austria
- Meryem Ralser
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Affiliation Max Planck Institute for Molecular Genetics, Department Vertebrate Genomics, Berlin, Germany
- Vyacheslav Amstislavskiy
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Affiliation Max Planck Institute for Molecular Genetics, Department Vertebrate Genomics, Berlin, Germany
- Julia Starmann
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Affiliation German Cancer Research Center, Heidelberg, Germany
- Ingrid Osprian
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Affiliations BIOCRATES Life Sciences AG, Innsbruck, Austria, LKH Wagna, Department of Internal Medicine, Wagna, Austria
- Christina Grimm
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Affiliation Rheumatology and Clinical Immunology, Charité-University Medicine, Berlin, Germany
- Hendrik Hache
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Affiliation Max Planck Institute for Molecular Genetics, Department Vertebrate Genomics, Berlin, Germany
- Marie-Laure Yaspo
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Affiliations Max Planck Institute for Molecular Genetics, Department Vertebrate Genomics, Berlin, Germany, Dahlem Centre for Genome Research and Medical Systems Biology, Berlin, Germany
- Holger Sültmann
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Affiliation German Cancer Research Center, Heidelberg, Germany
- Michael Trauner
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Affiliation Hans Popper Laboratory of Molecular Hepatology, Division of Gastroenterology and Hepatology, Department of Medicine, Medical University of Vienna, Vienna, Austria
- Helmut Denk
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Affiliation Institute of Pathology, Medical University of Graz, Graz, Austria
- Kurt Zatloukal
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Affiliation Institute of Pathology, Medical University of Graz, Graz, Austria
- Hans Lehrach
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Affiliations Max Planck Institute for Molecular Genetics, Department Vertebrate Genomics, Berlin, Germany, Dahlem Centre for Genome Research and Medical Systems Biology, Berlin, Germany
- Christoph Wierling
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* E-mail: wierling@molgen.mpg.de
Affiliation Max Planck Institute for Molecular Genetics, Department Vertebrate Genomics, Berlin, Germany
Competing Interests
Co-author Ingrid Osprian was employed by BIOCRATES Life Sciences AG during the runtime of the IMGuS project where she did the metabolic analysis presented in this manuscript. There are no patents, products in development or marketed products to declare. This does not alter the authors' adherence to all the PLOS ONE policies on sharing data and materials.
Author Contributions
Conceived and designed the experiments: MS KK JS IO MLY HS MT KZ HL CW. Performed the experiments: VP MS KK JS IO. Analyzed the data: VP MS HD KZ KK MR VA JS IO CW. Contributed reagents/materials/analysis tools: MS KK JS IO HH CW. Wrote the paper: VP MS CG CW.