Long-Term Central and Effector SHIV-Specific Memory T Cell Responses Elicited after a Single Immunization with a Novel Lentivector DNA Vaccine

Géraldine Arrode-Brusés; Maha Moussa; Monique Baccard-Longere; François Villinger; Yahia Chebloune

doi:10.1371/journal.pone.0110883

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Open Access

Peer-reviewed

Research Article

Long-Term Central and Effector SHIV-Specific Memory T Cell Responses Elicited after a Single Immunization with a Novel Lentivector DNA Vaccine

Géraldine Arrode-Brusés,

Affiliation INRA, ANRS, Université Joseph Fourier, PAVAL Lab./Nanobio 2, UJF Grenoble, Grenoble, France
⨯
Maha Moussa,

Affiliation INRA, ANRS, Université Joseph Fourier, PAVAL Lab./Nanobio 2, UJF Grenoble, Grenoble, France
⨯
Monique Baccard-Longere,

Affiliation Institut de Biologie et Pathologie, Centre Hospitalo-Universitaire de Grenoble, Grenoble, France
⨯
François Villinger,

Affiliation Division of Pathology, Yerkes National Primate Research Center, Emory University, Atlanta, Georgia, United States of America
⨯
Yahia Chebloune

* E-mail: ychebloune@lyon.inra.fr

Affiliation INRA, ANRS, Université Joseph Fourier, PAVAL Lab./Nanobio 2, UJF Grenoble, Grenoble, France
⨯

Long-Term Central and Effector SHIV-Specific Memory T Cell Responses Elicited after a Single Immunization with a Novel Lentivector DNA Vaccine

Géraldine Arrode-Brusés,
Maha Moussa,
Monique Baccard-Longere,
François Villinger,
Yahia Chebloune

Published: October 22, 2014
https://doi.org/10.1371/journal.pone.0110883

About the Authors

Géraldine Arrode-Brusés

Affiliation INRA, ANRS, Université Joseph Fourier, PAVAL Lab./Nanobio 2, UJF Grenoble, Grenoble, France

Maha Moussa

Affiliation INRA, ANRS, Université Joseph Fourier, PAVAL Lab./Nanobio 2, UJF Grenoble, Grenoble, France

Monique Baccard-Longere

Affiliation Institut de Biologie et Pathologie, Centre Hospitalo-Universitaire de Grenoble, Grenoble, France

François Villinger

Affiliation Division of Pathology, Yerkes National Primate Research Center, Emory University, Atlanta, Georgia, United States of America

Yahia Chebloune

* E-mail: ychebloune@lyon.inra.fr

Affiliation INRA, ANRS, Université Joseph Fourier, PAVAL Lab./Nanobio 2, UJF Grenoble, Grenoble, France

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: GAB YC. Performed the experiments: GAB MM. Analyzed the data: GAB MM YC. Contributed reagents/materials/analysis tools: MBL FV. Contributed to the writing of the manuscript: GAB YC FV.

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T cells
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Macaque
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Cytotoxic T cells
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Immune response
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HIV vaccines
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Enzyme-linked immunoassays
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SIV
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DNA vaccination
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