Preventive Effect of Yuzu and Hesperidin on Left Ventricular Remodeling and Dysfunction in Rat Permanent Left Anterior Descending Coronary Artery Occlusion Model

Hye Yon Yu; Ji Hun Ahn; Se Won Park; Yi-Sook Jung

doi:10.1371/journal.pone.0110596

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Open Access

Peer-reviewed

Research Article

Preventive Effect of Yuzu and Hesperidin on Left Ventricular Remodeling and Dysfunction in Rat Permanent Left Anterior Descending Coronary Artery Occlusion Model

Hye Yon Yu,

Affiliations Department of Physiology, School of Medicine, Ajou University, Suwon, Republic of Korea, College of Pharmacy, Ajou University, Suwon, Republic of Korea
⨯
Ji Hun Ahn,

Affiliation Department of Cardiology, Soon Chun Hyang University Gumi Hospital, Gumi, Republic of Korea
⨯
Se Won Park,

Affiliation Molecular Biotechnology, College of Life and Environmental Sciences, Konkuk University, Seoul, Republic of Korea
⨯
Yi-Sook Jung

* E-mail: yisjung@ajou.ac.kr

Affiliations College of Pharmacy, Ajou University, Suwon, Republic of Korea, Research Institute of Pharmaceutical Sciences and Technology, Ajou University, Suwon, Republic of Korea
⨯

Preventive Effect of Yuzu and Hesperidin on Left Ventricular Remodeling and Dysfunction in Rat Permanent Left Anterior Descending Coronary Artery Occlusion Model

Hye Yon Yu,
Ji Hun Ahn,
Se Won Park,
Yi-Sook Jung

Published: January 5, 2015
https://doi.org/10.1371/journal.pone.0110596

About the Authors

Hye Yon Yu

Affiliations Department of Physiology, School of Medicine, Ajou University, Suwon, Republic of Korea, College of Pharmacy, Ajou University, Suwon, Republic of Korea

Ji Hun Ahn

Affiliation Department of Cardiology, Soon Chun Hyang University Gumi Hospital, Gumi, Republic of Korea

Se Won Park

Affiliation Molecular Biotechnology, College of Life and Environmental Sciences, Konkuk University, Seoul, Republic of Korea

Yi-Sook Jung

* E-mail: yisjung@ajou.ac.kr

Affiliations College of Pharmacy, Ajou University, Suwon, Republic of Korea, Research Institute of Pharmaceutical Sciences and Technology, Ajou University, Suwon, Republic of Korea

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: HYY YSJ. Performed the experiments: HYY JHA. Analyzed the data: HYY JHA YSJ. Contributed reagents/materials/analysis tools: SWP YSJ. Wrote the paper: HYY YSJ.

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Myocardial infarction
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Apoptosis
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Cardiomyocytes
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Fibrosis
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Inflammation
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Fibroblasts
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Muscle cells
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Quantitative analysis
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