About the Authors

Yue Wang

Contributed equally to this work with: Yue Wang, Shijie Jin

Affiliation Department of Neuroimmunology, Research Institute of Environmental Medicine, Nagoya University, Nagoya, Japan

Shijie Jin

Contributed equally to this work with: Yue Wang, Shijie Jin

Affiliation Department of Neuroimmunology, Research Institute of Environmental Medicine, Nagoya University, Nagoya, Japan

Yoshifumi Sonobe

Affiliation Department of Neuroimmunology, Research Institute of Environmental Medicine, Nagoya University, Nagoya, Japan

Yi Cheng

Affiliation Department of Neuroimmunology, Research Institute of Environmental Medicine, Nagoya University, Nagoya, Japan

Hiroshi Horiuchi

Affiliation Department of Neuroimmunology, Research Institute of Environmental Medicine, Nagoya University, Nagoya, Japan

Bijay Parajuli

Affiliation Department of Neuroimmunology, Research Institute of Environmental Medicine, Nagoya University, Nagoya, Japan

Jun Kawanokuchi

Affiliation Department of Neuroimmunology, Research Institute of Environmental Medicine, Nagoya University, Nagoya, Japan

Tetsuya Mizuno

Affiliation Department of Neuroimmunology, Research Institute of Environmental Medicine, Nagoya University, Nagoya, Japan

Hideyuki Takeuchi

htake@riem.nagoya-u.ac.jp

Affiliation Department of Neuroimmunology, Research Institute of Environmental Medicine, Nagoya University, Nagoya, Japan

Akio Suzumura

Affiliation Department of Neuroimmunology, Research Institute of Environmental Medicine, Nagoya University, Nagoya, Japan

Competing Interests

Akio Suzumura is a PLOS ONE Editorial Board member. This does not alter the authors’ adherence to PLOS ONE Editorial policies and criteria.

Author Contributions

Conceived and designed the experiments: HT YS AS. Performed the experiments: YW SJ YS. Analyzed the data: YW HT SY TM. Contributed reagents/materials/analysis tools: YC HH BP JK. Contributed to the writing of the manuscript: YW HT AS.