About the Authors

Chunwei Zhang

Affiliations Hamilton Glaucoma Center and Department of Ophthalmology, University of California San Diego, San Diego, California, United States of America, Department of Ophthalmology, the First Affiliated Hospital, Harbin Medical University, Harbin, China

Andrew J. Tatham

Affiliation Hamilton Glaucoma Center and Department of Ophthalmology, University of California San Diego, San Diego, California, United States of America

Felipe A. Medeiros

Affiliation Hamilton Glaucoma Center and Department of Ophthalmology, University of California San Diego, San Diego, California, United States of America

Linda M. Zangwill

Affiliation Hamilton Glaucoma Center and Department of Ophthalmology, University of California San Diego, San Diego, California, United States of America

Zhiyong Yang

Affiliation Hamilton Glaucoma Center and Department of Ophthalmology, University of California San Diego, San Diego, California, United States of America

Robert N. Weinreb

rweinreb@ucsd.edu

Affiliation Hamilton Glaucoma Center and Department of Ophthalmology, University of California San Diego, San Diego, California, United States of America

Competing Interests

We wish to disclose the following competing interests: Chunwei Zhang: None. Andrew J. Tatham: Research Support; Heidelberg Engineering, GmbH. Felipe A. Medeiros: Funding; Alcon Laboratories, Bausch & Lomb, Carl Zeiss Meditec, Heidelberg Engineering, GmbH, Merck, Allergan, Sensimed, Topcon, Reichert, National Eye Institute. Research Support: Alcon Laboratories, Allergan, Carl Zeiss Meditec, Reichert, Consultant: Allergan, Carl-Zeiss Meditec, Novartis. Linda M. Zangwill: Funding; Carl Zeiss Meditec, Heidelberg Engineering, GmbH, Optovue, Topcon Medical Systems, Nidek. Zhiyong Yang: None. Robert N. Weinreb: Funding; Aerie, Carl Zeiss Meditec, Genentech, Heidelberg Engineering GmbH, National Eye Institute, Nidek, Novartis, Optovue, Quark, Topcon. Consultant; Alcon, Allergan, Bausch & Lomb, Carl Zeiss Meditec, Sensimed, Topcon. This does not alter the authors' adherence to PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: CZ AJT FAM LMZ ZY RNW. Performed the experiments: CZ. Analyzed the data: CZ AJT FAM ZY RNW. Wrote the paper: ZA AJT FAM LMZ RNW.