About the Authors

Nicholas M. Durham

Affiliation Department of Oncology, The Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America

Christopher J. Nirschl

Affiliation Department of Oncology, The Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America

Christopher M. Jackson

Affiliation Department of Oncology, The Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America

Jimmy Elias

Affiliation Department of Oncology, The Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America

Christina M. Kochel

Affiliation Department of Oncology, The Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America

Robert A. Anders

Affiliations Department of Oncology, The Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America, Department of Pathology, The Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America

Charles G. Drake

cdrake@jhmi.edu

Affiliation Department of Oncology, The Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America

Competing Interests

CGD has served as a paid consultant for Bristol Myers Squibb, Compugen and Roche/Genentech. CGD is a co-inventor on a patent entitled: “Manipulation of Regulatory T Cells Using LAG-3 Antibodies, Genes, Agonists and Antagonists”, filing case number: C04255. This patent is currently un-licensed. This does not alter the authors’ adherence to PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: NMD CJN CGD. Performed the experiments: NMD CJN CMJ JE CMK RAA. Analyzed the data: NMD. Contributed reagents/materials/analysis tools: NMD. Wrote the paper: NMD CGD.