About the Authors

Taku Murakami

Affiliation Hitachi Chemical Research Center, Inc., Irvine, California, United States of America

Melanie Oakes

Affiliations Hitachi Chemical Research Center, Inc., Irvine, California, United States of America, Genomics High-Throughput Facility, University of California Irvine, Irvine, California, United States of America

Mieko Ogura

Affiliation Hitachi Chemical Research Center, Inc., Irvine, California, United States of America

Vivian Tovar

Affiliation Hitachi Chemical Research Center, Inc., Irvine, California, United States of America

Cindy Yamamoto

Affiliation Hitachi Chemical Research Center, Inc., Irvine, California, United States of America

Masato Mitsuhashi

mitsuhashiconsultant@HCRcenter.com

Affiliations Hitachi Chemical Research Center, Inc., Irvine, California, United States of America, NanoSomiX, Inc., Irvine, California, United States of America

Competing Interests

The authors have the following interests: This study was funded by Hitachi Chemical Research Center, Inc (HCR). TM, M Oakes, M Ogura, VT and CY are employees of HCR, Inc. and MM is a consultant of HCR. MM is a founder and CTO of NanoSomiX, Inc. M Ogura and/or MM have filed the following patent applications related with this study: PCT/US2013/063114 (SYSTEMS AND METHODS AND DEVICES FOR CAPTURE AND CONCENTRATION OF AGENTS OF INTEREST FROM FLUID SAMPLES), WO2011/156763 (METHODS FOR CHARACTERIZING KIDNEY FUNCTION), WO2011/156763 (Vesicle Capturing Devices and Methods for using Same and) and WO2014/055687 (URINE EXOSOME mRNAs AND METHODS OF USING SAME TO DETECT DIABETIC NEPHROPATHY). This does not alter the authors' adherence to PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: TM M. Oakes MM. Performed the experiments: TM M. Oakes MM. Analyzed the data: TM M. Oakes CY MM. Contributed reagents/materials/analysis tools: TM M. Oakes M. Ogura VT CY MM. Wrote the paper: TM M. Oakes CY MM.