Ability of Nafamostat Mesilate to Prolong Filter Patency during Continuous Renal Replacement Therapy in Patients at High Risk of Bleeding: A Randomized Controlled Study

Yong Kyu Lee; Hae Won Lee; Kyu Hun Choi; Beom Seok Kim

doi:10.1371/journal.pone.0108737

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Open Access

Peer-reviewed

Research Article

Ability of Nafamostat Mesilate to Prolong Filter Patency during Continuous Renal Replacement Therapy in Patients at High Risk of Bleeding: A Randomized Controlled Study

Yong Kyu Lee,

Affiliation Nephrology Division, Internal Medicine Department, National Health Institute Corporation, Ilsan Hospital, Goyang, Republic of Korea
⨯
Hae Won Lee,

Affiliation Nephrology Division, Department of Internal Medicine, Severance Hospital, Yonsei University College of Medicine, Seoul, Republic of Korea
⨯
Kyu Hun Choi,

Affiliation Nephrology Division, Department of Internal Medicine, Severance Hospital, Yonsei University College of Medicine, Seoul, Republic of Korea
⨯
Beom Seok Kim

* E-mail: docbsk@yuhs.ac

Affiliation Nephrology Division, Department of Internal Medicine, Severance Hospital, Yonsei University College of Medicine, Seoul, Republic of Korea
⨯

Ability of Nafamostat Mesilate to Prolong Filter Patency during Continuous Renal Replacement Therapy in Patients at High Risk of Bleeding: A Randomized Controlled Study

Yong Kyu Lee,
Hae Won Lee,
Kyu Hun Choi,
Beom Seok Kim

Published: October 10, 2014
https://doi.org/10.1371/journal.pone.0108737

About the Authors

Yong Kyu Lee

Affiliation Nephrology Division, Internal Medicine Department, National Health Institute Corporation, Ilsan Hospital, Goyang, Republic of Korea

Hae Won Lee

Affiliation Nephrology Division, Department of Internal Medicine, Severance Hospital, Yonsei University College of Medicine, Seoul, Republic of Korea

Kyu Hun Choi

Affiliation Nephrology Division, Department of Internal Medicine, Severance Hospital, Yonsei University College of Medicine, Seoul, Republic of Korea

Beom Seok Kim

* E-mail: docbsk@yuhs.ac

Affiliation Nephrology Division, Department of Internal Medicine, Severance Hospital, Yonsei University College of Medicine, Seoul, Republic of Korea

Competing Interests

This study was funded by SK chemical and Yonsei University College of Medicine. However this does not alter the authors' adherence to PLOS one policies on sharing data and materials.

Author Contributions

Wrote the paper: YKL BSK. Conceived and designed the experiments: BSK. Performed the experiments: HWL. Analyzed the data: YKL. Contributed reagents/materials/analysis tools: KHC BSK.

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Hemorrhage
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Adverse events
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Blood transfusion
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Medical risk factors
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Gastrointestinal infections
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Heparin
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Platelets
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Gynecologic infections
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