About the Authors

Tsukasa Shigehiro

Contributed equally to this work with: Tsukasa Shigehiro, Tomonari Kasai

Affiliation Department of Biotechnology, Graduate School of Natural Science and Technology, Okayama University, Okayama, Japan

Tomonari Kasai

Contributed equally to this work with: Tsukasa Shigehiro, Tomonari Kasai

Affiliation Department of Biotechnology, Graduate School of Natural Science and Technology, Okayama University, Okayama, Japan

Masaharu Murakami

Affiliation Department of Biotechnology, Graduate School of Natural Science and Technology, Okayama University, Okayama, Japan

Sreeja C. Sekhar

Affiliation Department of Biotechnology, Graduate School of Natural Science and Technology, Okayama University, Okayama, Japan

Yuki Tominaga

Affiliation Department of Biotechnology, Graduate School of Natural Science and Technology, Okayama University, Okayama, Japan

Masashi Okada

Affiliation Department of Biotechnology, Graduate School of Natural Science and Technology, Okayama University, Okayama, Japan

Takayuki Kudoh

Affiliation Department of Biotechnology, Graduate School of Natural Science and Technology, Okayama University, Okayama, Japan

Akifumi Mizutani

Affiliation Department of Biotechnology, Graduate School of Natural Science and Technology, Okayama University, Okayama, Japan

Hiroshi Murakami

Affiliation Department of Biotechnology, Graduate School of Natural Science and Technology, Okayama University, Okayama, Japan

David S. Salomon

Affiliation Mouse Cancer Genetics Program, Center for Cancer Research, National Cancer Institute, Frederick, Maryland, United States of America

Katsuhiko Mikuni

Affiliation Ensuiko Sugar Refining Co., Ltd., Tokyo, Japan

Tadakatsu Mandai

Affiliation Faculty of Life Science, Kurashiki University of Science and the Arts, Kurashiki, Japan

Hiroki Hamada

hamada@dls.ous.ac.jp (HH); mseno@okayama-u.ac.jp (MS)

Affiliation Faculty of Science, Okayama University of Science, Okayama, Japan

Masaharu Seno

hamada@dls.ous.ac.jp (HH); mseno@okayama-u.ac.jp (MS)

Affiliation Department of Biotechnology, Graduate School of Natural Science and Technology, Okayama University, Okayama, Japan

Competing Interests

The authors of this manuscript have read the journal's policy and have the following competing interests: This study was funded by a commercial company (Ensuiko Sugar Refining Co., Ltd.) and one of the authors, Katsuhiko Mikuni, is an employee of Ensuiko Sugar Refining Co., Ltd.. Trastuzumab was gifted from a commercial company (Chugai pharmaceutical. Co., LTD.). Okayama University, Ensuiko Sugar Refining Co., Ltd., and Hiroki Hamada are the applicants of the publication Japanese Patent No. 5490326 and the international patent application No. PCT/JP2013/058242 titled “Method for producing liposome encapsulating paclitaxel monoglycoside and/or docetaxel monoglycoside”. Masaharu Seno is an academic editor of PLOS ONE. These do not alter the authors' adherence to all of the PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: TS T. Kasai KM HH MS. Performed the experiments: TS T. Kasai MM YT. Analyzed the data: TS SCS MO. Contributed reagents/materials/analysis tools: T. Kudoh AM HM TM. Wrote the paper: TS MS. Data discussion and manuscript revision: DSS.