About the Authors

Norikazu Hinamoto

Affiliation Department of Medicine and Clinical Science, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan

Yohei Maeshima

ymaeshim@md.okayama-u.ac.jp

Affiliation Department of Chronic Kidney Disease and Cardiovascular Disease, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan

Hiroko Yamasaki

Affiliation Department of Medicine and Clinical Science, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan

Tatsuyo Nasu

Affiliation Department of Medicine and Clinical Science, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan

Daisuke Saito

Affiliation Department of Medicine and Clinical Science, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan

Hiroyuki Watatani

Affiliation Department of Medicine and Clinical Science, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan

Haruyo Ujike

Affiliation Department of Medicine and Clinical Science, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan

Katsuyuki Tanabe

Affiliation Department of Medicine and Clinical Science, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan

Kana Masuda

Affiliation Department of Medicine and Clinical Science, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan

Yuka Arata

Affiliation Department of Medicine and Clinical Science, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan

Hitoshi Sugiyama

Affiliation Department of Chronic Kidney Disease and Peritoneal Dialysis, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan

Yasufumi Sato

Affiliation Department of Vascular Biology, Institute of Development, Aging, and Cancer, Tohoku University, Sendai, Japan

Hirofumi Makino

Affiliation Department of Medicine and Clinical Science, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan

Competing Interests

The authors have read the journal’s policy and the authors of this manuscript have the following competing interests: Prof. Yohei Maeshima belongs to endowed department by Chugai pharmaceutical, MSD, Boehringer ingelheim and Kawanishi Holdings. Prof. Hitoshi Sugiyama belongs to endowed department by Baxter. Prof. Hirofumi Makino is a consultant for AbbVie, Astellas and Teijin, receives speaker honoraria from Astellas, Boehringer-ingelheim, Chugai, Daiichi Sankyo, Dainippon Sumitomo, Kyowa Hakko Kirin, MSD, Novartis, Pfizer, Takeda and Tanabe Mitsubishi, and receives grant support from Astellas, Boehringer-ingelheim, Daiichi Sankyo, Dainippon Sumitomo, Kyowa Hakko Kirin, Mochida, MSD, Novartis, Novo Nordisk, Pfizer, Takeda and Tanabe Mitsubishi. Any other authors don’t have competing interests. This does not alter the authors’ adherence to PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: NH YM. Performed the experiments: NH HY TN DS HW HU KT KM YA. Analyzed the data: NH YM. Contributed reagents/materials/analysis tools: NH DS YM. Contributed to the writing of the manuscript: NH YM HM HS YS.