About the Authors

Oguz Kilickaya

Affiliation Multidisciplinary Epidemiology and Translational Research in intensive care, emergency and perioperative Medicine (METRIC), Division of Pulmonary and Critical Care Medicine, Department of Medicine, Mayo Clinic, Rochester, Minnesota, United States of America

Christopher Schmickl

Affiliations Multidisciplinary Epidemiology and Translational Research in intensive care, emergency and perioperative Medicine (METRIC), Division of Pulmonary and Critical Care Medicine, Department of Medicine, Mayo Clinic, Rochester, Minnesota, United States of America, University Witten-Herdecke, Witten, Germany

Adil Ahmed

Affiliation Multidisciplinary Epidemiology and Translational Research in intensive care, emergency and perioperative Medicine (METRIC), Division of Pulmonary and Critical Care Medicine, Department of Medicine, Mayo Clinic, Rochester, Minnesota, United States of America

Juan Pulido

Affiliations Multidisciplinary Epidemiology and Translational Research in intensive care, emergency and perioperative Medicine (METRIC), Division of Pulmonary and Critical Care Medicine, Department of Medicine, Mayo Clinic, Rochester, Minnesota, United States of America, Division of Critical Care, Department of Anesthesiology, Mayo Clinic, Rochester, Minnesota, United States of America

James Onigkeit

Affiliations Multidisciplinary Epidemiology and Translational Research in intensive care, emergency and perioperative Medicine (METRIC), Division of Pulmonary and Critical Care Medicine, Department of Medicine, Mayo Clinic, Rochester, Minnesota, United States of America, Division of Critical Care, Department of Anesthesiology, Mayo Clinic, Rochester, Minnesota, United States of America

Kianoush Kashani

Affiliations Division of Pulmonary and Critical Care, Department of Medicine, Mayo Clinic, Rochester, Minnesota, United States of America, Division of Nephrology and Hypertension, Department of Medicine, Mayo Clinic, Rochester, Minnesota, United States of America

Ognjen Gajic

Affiliations Multidisciplinary Epidemiology and Translational Research in intensive care, emergency and perioperative Medicine (METRIC), Division of Pulmonary and Critical Care Medicine, Department of Medicine, Mayo Clinic, Rochester, Minnesota, United States of America, Division of Critical Care, Department of Anesthesiology, Mayo Clinic, Rochester, Minnesota, United States of America

Vitaly Herasevich

Affiliations Multidisciplinary Epidemiology and Translational Research in intensive care, emergency and perioperative Medicine (METRIC), Division of Pulmonary and Critical Care Medicine, Department of Medicine, Mayo Clinic, Rochester, Minnesota, United States of America, Division of Critical Care, Department of Anesthesiology, Mayo Clinic, Rochester, Minnesota, United States of America

Brian Pickering

Pickering.Brian@mayo.edu

Affiliations Multidisciplinary Epidemiology and Translational Research in intensive care, emergency and perioperative Medicine (METRIC), Division of Pulmonary and Critical Care Medicine, Department of Medicine, Mayo Clinic, Rochester, Minnesota, United States of America, Division of Critical Care, Department of Anesthesiology, Mayo Clinic, Rochester, Minnesota, United States of America

Competing Interests

This research has been reviewed by the Mayo Clinic Conflict of Interest Review Board and is being conducted in compliance with Mayo Clinic Conflict of Interest policies. This publication was supported by Grant Number UL1 TR000135 from the National Center for Advancing Translational Sciences (NCATS). Its contents are solely the responsibility of the authors and do not necessarily represent the official views of the NIH. Mayo Clinic and authors (OG, VH, BWP) hold the patent application on AWARE technology referenced in this paper (US 2010/0198622, 12/697861, PCT/US2010/022750). AWARE is licensed to Ambient Clinical Analytics Inc. Dr Pickering additionally serves as member on the Board of Directors of Ambient Clinical Analytics Inc. Dr. Kilickaya reports grant support (UL1 TR000135) from the National Center for Advancing Translational Sciences (NCATS, http://www.ncats.nih.gov/) during the conduct of the study. This does not alter the authors’ adherence to PLOS ONE Editorial policies and criteria. The other authors have nothing to disclose.

Author Contributions

Conceived and designed the experiments: OK AA BP OG VH. Performed the experiments: OK JP JO KK VH. Analyzed the data: OK CS. Contributed to the writing of the manuscript: OK CS. Revised the manuscript: OK CS AA JP JO KK BP OG VH.