About the Authors

Amy R. Noe

Contributed equally to this work with: Amy R. Noe, Diego Espinosa

Affiliation Leidos Inc., Frederick, Maryland, United States of America

Diego Espinosa

Contributed equally to this work with: Amy R. Noe, Diego Espinosa

Affiliation Johns Hopkins Malaria Research Institute and Department of Molecular Microbiology and Immunology, Johns Hopkins Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland, United States of America

Xiangming Li

Affiliation HIV and Malaria Vaccine Program, Aaron Diamond AIDS Research Center, Affiliate of The Rockefeller University, New York, New York, United States of America

Jordana G. A. Coelho-dos-Reis

Affiliation HIV and Malaria Vaccine Program, Aaron Diamond AIDS Research Center, Affiliate of The Rockefeller University, New York, New York, United States of America

Ryota Funakoshi

Affiliation HIV and Malaria Vaccine Program, Aaron Diamond AIDS Research Center, Affiliate of The Rockefeller University, New York, New York, United States of America

Steve Giardina

Affiliation Leidos Inc., Frederick, Maryland, United States of America

Hongfan Jin

Affiliation Pfenex Inc., San Diego, California, United States of America

Diane M. Retallack

Affiliation Pfenex Inc., San Diego, California, United States of America

Ryan Haverstock

Affiliation Pfenex Inc., San Diego, California, United States of America

Jeffrey R. Allen

Affiliation Pfenex Inc., San Diego, California, United States of America

Thomas S. Vedvick

Affiliation Infectious Disease Research Institute, Seattle, Washington, United States of America

Christopher B. Fox

Affiliation Infectious Disease Research Institute, Seattle, Washington, United States of America

Steven G. Reed

Affiliation Infectious Disease Research Institute, Seattle, Washington, United States of America

Ramses Ayala

Affiliation Leidos Inc., Frederick, Maryland, United States of America

Brian Roberts

Affiliation Leidos Inc., Frederick, Maryland, United States of America

Scott B. Winram

Affiliation Leidos Inc., Frederick, Maryland, United States of America

John Sacci

Affiliation Department of Microbiology and Immunology, University of Maryland School of Medicine, Baltimore, Maryland, United States of America

Moriya Tsuji

Affiliation HIV and Malaria Vaccine Program, Aaron Diamond AIDS Research Center, Affiliate of The Rockefeller University, New York, New York, United States of America

Fidel Zavala

Affiliation Johns Hopkins Malaria Research Institute and Department of Molecular Microbiology and Immunology, Johns Hopkins Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland, United States of America

Gabriel M. Gutierrez

gabriel.m.gutierrez@leidos.com

Affiliation Leidos Inc., Frederick, Maryland, United States of America

Competing Interests

The authors declare the following interests: Co-authors Amy R. Noe, Steve Giardina, Ramses Ayala, Brian Roberts, Scott B. Winram and Gabriel M. Gutierrez are employed by Leidos Inc. Co-authors Hongfan Jin, Diane Retallack, Ryan Haverstock and Jeff Allen are employed by Pfenex Inc. Co-author Moriya Tsuji is an Academic Editor for PLOS ONE. The Pseudomonas expression platform is patented by Pfenex, Inc. and rCSP is being developed for clinical trials. There are no marketed products to declare. This does not alter the authors' adherence to all the PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: ARN RH JRA BR SBW JS MT FZ GMG. Analyzed the data: ARN DE XL JGAC RF SG RA JS MT FZ GMG. Contributed reagents/materials/analysis tools: ARN DE XL JGAC RF HJ DMR RH JRA TSV CBF SGR JS MT FZ GMG. Wrote the paper: ARN DE SG RA MT FZ GMG.