About the Authors
- Victoria L. Newton
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Affiliation Faculty of Life Sciences, University of Manchester, Manchester, United Kingdom
- Sumia Ali
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Affiliation Faculty of Life Sciences, University of Manchester, Manchester, United Kingdom
- Graham Duddy
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Current address: The Wellcome Trust Sanger Institute, Hinxton, Cambridge, United Kingdom
Affiliation Platform Technology and Sciences, GlaxoSmithKline, Stevenage, Herts, United Kingdom
- Alan J. Whitmarsh
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Affiliation Faculty of Life Sciences, University of Manchester, Manchester, United Kingdom
- Natalie J. Gardiner
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* E-mail: natalie.gardiner@manchester.ac.uk
Affiliation Faculty of Life Sciences, University of Manchester, Manchester, United Kingdom
Competing Interests
This work was supported by a GlaxoSmithKline(GSK)-BBSRC(UK) PhD studentship (VLN). The authors thank GSK for advice, the supply of ASK1n mice and consumable support. This does not alter the authors' adherence to PLOS ONE policies on sharing data. The ASK1 transgenic mice were generated using patented technologies and as a result of licence restrictions are not available to non-collaborators.
Author Contributions
Conceived and designed the experiments: NJG VLN SA AJW. Performed the experiments: VLN SA. Analyzed the data: VLN SA. Contributed reagents/materials/analysis tools: GD. Wrote the paper: VLN SA NJG.