About the Authors

Takashi Ito

tito@huhs.ac.jp (TI); azuma@huhs.ac.jp (JA)

Affiliation College of Pharmacy, Department of Clinical Pharmacogenomics, Hyogo University of Health Sciences, Kobe, Hyogo, Japan

Natsumi Yoshikawa

Affiliation College of Pharmacy, Department of Clinical Pharmacogenomics, Hyogo University of Health Sciences, Kobe, Hyogo, Japan

Takaaki Inui

Affiliation College of Pharmacy, Department of Clinical Pharmacogenomics, Hyogo University of Health Sciences, Kobe, Hyogo, Japan

Natsuko Miyazaki

Affiliation College of Pharmacy, Department of Clinical Pharmacogenomics, Hyogo University of Health Sciences, Kobe, Hyogo, Japan

Stephen W. Schaffer

Affiliation College of Medicine, Department of Pharmacology, University of South Alabama, Mobile, Alabama, United States of America

Junichi Azuma

tito@huhs.ac.jp (TI); azuma@huhs.ac.jp (JA)

Affiliation College of Pharmacy, Department of Clinical Pharmacogenomics, Hyogo University of Health Sciences, Kobe, Hyogo, Japan

Competing Interests

This work was partially supported by a research grant from Taisho Phamaceutical Co. Ltd for JA. This does not alter the authors’ adherence to all PLOS ONE policies on sharing data and materials. The other authors do not have a financial interest related to this work.

Author Contributions

Conceived and designed the experiments: T. Ito. Performed the experiments: T. Ito NM NY T. Inui. Analyzed the data: T. Ito. Contributed to the writing of the manuscript: T. Ito SWS JA.