About the Authors

Katharine A. Michie

Contributed equally to this work with: Katharine A. Michie, Anders Boysen, Harry H. Low

Current address: School of Molecular Biosciences, The University of Sydney, Sydney, Australia

Affiliation MRC Laboratory of Molecular Biology, Structural Studies Division, Cambridge, United Kingdom

Anders Boysen

Contributed equally to this work with: Katharine A. Michie, Anders Boysen, Harry H. Low

Affiliation Department of Biochemistry and Molecular Biology, University of Southern Denmark, Odense M, Denmark

Harry H. Low

Contributed equally to this work with: Katharine A. Michie, Anders Boysen, Harry H. Low

Current address: Department of Life Sciences, Imperial College, London, United Kingdom

Affiliation MRC Laboratory of Molecular Biology, Structural Studies Division, Cambridge, United Kingdom

Jakob Møller-Jensen

Affiliation Department of Biochemistry and Molecular Biology, University of Southern Denmark, Odense M, Denmark

Jan Löwe

jyl@mrc-lmb.cam.ac.uk

Affiliation MRC Laboratory of Molecular Biology, Structural Studies Division, Cambridge, United Kingdom

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: KAM AB HHL JMJ JL. Performed the experiments: KAM AB HHL. Analyzed the data: KAM AB HHL JMJ JL. Wrote the paper: KAM HHL JL. First recognised LeoB/C similarity to dynamins, optimised LeoA crystals, built and refined LeoA crystal structure, made constructs for EM, purified untagged LeoA, GTPase and binding assays, lipid binding assays: KAM. Performed all in vivo experiments: AB. First recognised LeoA similarity to dynamins and purified and crystallised LeoA: HHL.