Antibacterial Compounds of Canadian Honeys Target Bacterial Cell Wall Inducing Phenotype Changes, Growth Inhibition and Cell Lysis That Resemble Action of β-Lactam Antibiotics

Katrina Brudzynski; Calvin Sjaarda

doi:10.1371/journal.pone.0106967

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Open Access

Peer-reviewed

Research Article

Antibacterial Compounds of Canadian Honeys Target Bacterial Cell Wall Inducing Phenotype Changes, Growth Inhibition and Cell Lysis That Resemble Action of β-Lactam Antibiotics

Katrina Brudzynski ,

* E-mail: beebio@sympatico.ca

Affiliation Bee-Biomedicals Inc., Drug Discovery and Development Department, St. Catharines, Ontario, Canada
⨯
Calvin Sjaarda

Affiliation Bee-Biomedicals Inc., Drug Discovery and Development Department, St. Catharines, Ontario, Canada
⨯

Antibacterial Compounds of Canadian Honeys Target Bacterial Cell Wall Inducing Phenotype Changes, Growth Inhibition and Cell Lysis That Resemble Action of β-Lactam Antibiotics

Katrina Brudzynski,
Calvin Sjaarda

Published: September 5, 2014
https://doi.org/10.1371/journal.pone.0106967

About the Authors

Katrina Brudzynski

* E-mail: beebio@sympatico.ca

Affiliation Bee-Biomedicals Inc., Drug Discovery and Development Department, St. Catharines, Ontario, Canada

Calvin Sjaarda

Affiliation Bee-Biomedicals Inc., Drug Discovery and Development Department, St. Catharines, Ontario, Canada

Competing Interests

KB and CS are employees of Bee-Biomedicals Inc. There are no patents, products in development or marketed products to declare. The authors adhere to all the PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: KB CS. Performed the experiments: KB CS. Analyzed the data: KB CS. Contributed reagents/materials/analysis tools: KB CS. Contributed to the writing of the manuscript: KB CS.

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Honey
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Cell walls
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Endotoxins
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Antibacterials
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Lysis (medicine)
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Membrane staining
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Antibiotics
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Cell staining
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