About the Authors

Katrin Sippel

Contributed equally to this work with: Katrin Sippel, Enkelejda Kasneci

Affiliation Computer Engineering Department, University of Tübingen, Tübingen, Germany

Enkelejda Kasneci

Contributed equally to this work with: Katrin Sippel, Enkelejda Kasneci

enkelejda.kasneci@uni-tuebingen.de

Affiliation Computer Engineering Department, University of Tübingen, Tübingen, Germany

Kathrin Aehling

Affiliation Centre for Ophthalmology, Institute for Ophthalmic Research, University of Tübingen, Tübingen, Germany

Martin Heister

Affiliation Centre for Ophthalmology, Institute for Ophthalmic Research, University of Tübingen, Tübingen, Germany

Wolfgang Rosenstiel

Affiliation Computer Engineering Department, University of Tübingen, Tübingen, Germany

Ulrich Schiefer

Affiliations Centre for Ophthalmology, Institute for Ophthalmic Research, University of Tübingen, Tübingen, Germany, Competence Centre “Vision Research”, Study Course “Ophthalmic Optics/Audiology”, University of Applied Sciences Aalen, Aalen, Germany

Elena Papageorgiou

Affiliations Centre for Ophthalmology, Institute for Ophthalmic Research, University of Tübingen, Tübingen, Germany, Department of Ophthalmology, University of Leicester, Leicester Royal Infirmary, Leicester, United Kingdom

Competing Interests

The authors have the following interests. PFIZER Pharma GmbH, Berlin, Germany, and MSD, SHARP & DOHME GmbH, Haar, Germany provided financial support to this study. There are no patents, products in development or marketed products to declare. This does not alter the authors’ adherence to all the PLOS ONE policies on sharing data and materials, as detailed online in the guide for authors.

Author Contributions

Conceived and designed the experiments: US EP KA MH. Performed the experiments: KS EK KA MH US. Analyzed the data: KS EK. Contributed reagents/materials/analysis tools: KS EK. Contributed to the writing of the manuscript: KS EK WR US EP.