About the Authors

J. Dinesh Kumar

Affiliation Department of Cell and Molecular Physiology, University of Liverpool, Liverpool, United Kingdom

Chris Holmberg

Affiliation Department of Cell and Molecular Physiology, University of Liverpool, Liverpool, United Kingdom

Sandhir Kandola

Affiliation Department of Cell and Molecular Physiology, University of Liverpool, Liverpool, United Kingdom

Islay Steele

Affiliation Department of Cell and Molecular Physiology, University of Liverpool, Liverpool, United Kingdom

Peter Hegyi

Affiliation Department of Medicine and Surgery, University of Szeged, Szeged, Hungary

Laszlo Tiszlavicz

Affiliation Department of Pathology, University of Szeged, Szeged, Hungary

Rosalind Jenkins

Affiliation Department of Pharmacology, Institute of Translational Medicine, University of Liverpool, Liverpool, United Kingdom

Robert J. Beynon

Affiliation Institute of Integrative Biology, University of Liverpool, Liverpool, United Kingdom

David Peeney

Affiliation Department of Cell and Molecular Physiology, University of Liverpool, Liverpool, United Kingdom

Olivier T. Giger

Affiliation Department of Cell and Molecular Physiology, University of Liverpool, Liverpool, United Kingdom

Ahlam Alqahtani

Affiliation Department of Cell and Molecular Physiology, University of Liverpool, Liverpool, United Kingdom

Timothy C. Wang

Affiliation Department of Medicine, Columbia University Medical Center, New York, United States of America

Trevor T. Charvat

Affiliation ChemoCentryx, California, United States of America

Mark Penfold

Affiliation ChemoCentryx, California, United States of America

Graham J. Dockray

Affiliation Department of Cell and Molecular Physiology, University of Liverpool, Liverpool, United Kingdom

Andrea Varro

avarro@liverpool.ac.uk

Affiliation Department of Cell and Molecular Physiology, University of Liverpool, Liverpool, United Kingdom

Competing Interests

TC and MP are remunerated employees of ChemoCentryx. This does not alter the authors' adherence to PLOS ONE policies on sharing data and materials. The other authors have no conflicts of interest.

Author Contributions

Conceived and designed the experiments: RJB TCW MP GJD AV. Performed the experiments: JDK CH SK IS PH LT RJ DP OTG AA TTC. Analyzed the data: JDK CH SK LT RJ GJD AV. Contributed reagents/materials/analysis tools: TTC MP PH. Contributed to the writing of the manuscript: JDK CH MP GJD AV.