Gas Chromatography Time-Of-Flight Mass Spectrometry (GC-TOF-MS)-Based Metabolomics for Comparison of Caffeinated and Decaffeinated Coffee and Its Implications for Alzheimer’s Disease

Kai Lun Chang; Paul C. Ho

doi:10.1371/journal.pone.0104621

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Open Access

Peer-reviewed

Research Article

Gas Chromatography Time-Of-Flight Mass Spectrometry (GC-TOF-MS)-Based Metabolomics for Comparison of Caffeinated and Decaffeinated Coffee and Its Implications for Alzheimer’s Disease

Kai Lun Chang,

Affiliation Department of Pharmacy, Faculty of Science, National University of Singapore, Singapore, Singapore
⨯
Paul C. Ho

* E-mail: phahocl@nus.edu.sg

Affiliation Department of Pharmacy, Faculty of Science, National University of Singapore, Singapore, Singapore
⨯

Gas Chromatography Time-Of-Flight Mass Spectrometry (GC-TOF-MS)-Based Metabolomics for Comparison of Caffeinated and Decaffeinated Coffee and Its Implications for Alzheimer’s Disease

Kai Lun Chang,
Paul C. Ho

Published: August 6, 2014
https://doi.org/10.1371/journal.pone.0104621

About the Authors

Kai Lun Chang

Affiliation Department of Pharmacy, Faculty of Science, National University of Singapore, Singapore, Singapore

Paul C. Ho

* E-mail: phahocl@nus.edu.sg

Affiliation Department of Pharmacy, Faculty of Science, National University of Singapore, Singapore, Singapore

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: KLC PCH. Performed the experiments: KLC. Analyzed the data: KLC. Contributed reagents/materials/analysis tools: PCH. Contributed to the writing of the manuscript: KLC. Reviewed the manuscript: PCH. Approved final version for publication: PCH.

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Metabolites
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Metabolomics
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Coffee
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Caffeine
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Alzheimer's disease
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Antioxidant therapy
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Phenols
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Principal component analysis
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