About the Authors

Richard M. Gibson

Contributed equally to this work with: Richard M. Gibson, Jan Weber

Affiliation University Hospital Translational Laboratory, University Hospitals Case Medical Center, Cleveland, Ohio, United States of America

Jan Weber

Contributed equally to this work with: Richard M. Gibson, Jan Weber

Affiliation Institute of Organic Chemistry and Biochemistry, Prague, Czech Republic

Dane Winner

Affiliation University Hospital Translational Laboratory, University Hospitals Case Medical Center, Cleveland, Ohio, United States of America

Michael D. Miller

Affiliation Gilead Sciences, Inc., Foster City, California, United States of America

Miguel E. Quiñones-Mateu

meq@case.edu

Affiliations University Hospital Translational Laboratory, University Hospitals Case Medical Center, Cleveland, Ohio, United States of America, Department of Pathology, Case Western Reserve University, Cleveland, Ohio, United States of America

Competing Interests

R.M.G. and M.E.Q.-M. developed the novel HIV-1 genotyping and coreceptor tropism assay, DEEPGEN HIV. M.D.M. is employed by Gilead Sciences, the developer of elvitegravir, which was used in this study. There are no further patents, products in development or marketed products to declare. This does not alter the authors' adherence to all the PLOS ONE policies on sharing data and materials, as detailed online in the guide for authors.

Author Contributions

Conceived and designed the experiments: MEQM. Performed the experiments: RMG JW DW. Analyzed the data: RMG JW MEQM. Contributed reagents/materials/analysis tools: MDM. Contributed to the writing of the manuscript: MEQM.