About the Authors

Alice E. Davidson

Contributed equally to this work with: Alice E. Davidson, Sek-Shir Cheong

Affiliation UCL Institute of Ophthalmology, London, United Kingdom

Sek-Shir Cheong

Contributed equally to this work with: Alice E. Davidson, Sek-Shir Cheong

Affiliation UCL Institute of Ophthalmology, London, United Kingdom

Pirro G. Hysi

Affiliation Department of Twin Research and Genetic Epidemiology, King's College London, St. Thomas' Hospital, London, United Kingdom

Cristina Venturini

Affiliation Department of Twin Research and Genetic Epidemiology, King's College London, St. Thomas' Hospital, London, United Kingdom

Vincent Plagnol

Affiliation UCL Genetics Institute, London, United Kingdom

Jonathan B. Ruddle

Affiliation Department of Ophthalmology, Centre for Eye Research, University of Melbourne, Melbourne, Victoria, Australia

Hala Ali

Affiliation UCL Institute of Ophthalmology, London, United Kingdom

Nicole Carnt

Affiliations UCL Institute of Ophthalmology, London, United Kingdom, Moorfields Eye Hospital, London, United Kingdom

Jessica C. Gardner

Affiliation UCL Institute of Ophthalmology, London, United Kingdom

Hala Hassan

Affiliations UCL Institute of Ophthalmology, London, United Kingdom, Moorfields Eye Hospital, London, United Kingdom

Else Gade

Affiliation Department of Ophthalmology, Odense University Hospital, Odense, Denmark

Lisa Kearns

Affiliation Department of Ophthalmology, Centre for Eye Research, University of Melbourne, Melbourne, Victoria, Australia

Anne Marie Jelsig

Affiliation Department of Clinical Genetics, Odense University Hospital, Odense, Denmark

Marie Restori

Affiliation Moorfields Eye Hospital, London, United Kingdom

Tom R. Webb

Affiliation UCL Institute of Ophthalmology, London, United Kingdom

David Laws

Affiliation Department of Ophthalmology, Singleton Hospital, Swansea, United Kingdom

Michael Cosgrove

Affiliation Department of Women and Child Health, Singleton Hospital, Swansea, United Kingdom

Jens M. Hertz

Affiliation Department of Clinical Genetics, Odense University Hospital, Odense, Denmark

Isabelle Russell-Eggitt

Affiliation Great Ormond Street Hospital for Children, London, United Kingdom

Daniela T. Pilz

Affiliation Institute of Medical Genetics, University Hospital of Wales, Cardiff, United Kingdom

Christopher J. Hammond

Affiliation Department of Twin Research and Genetic Epidemiology, King's College London, St. Thomas' Hospital, London, United Kingdom

Stephen J. Tuft

Affiliations UCL Institute of Ophthalmology, London, United Kingdom, Moorfields Eye Hospital, London, United Kingdom

Alison J. Hardcastle

a.hardcastle@ucl.ac.uk

Affiliation UCL Institute of Ophthalmology, London, United Kingdom

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: CJH SJT AJH AED S-SC PGH. Performed the experiments: AED S-SC HA PGH CV VP. Analyzed the data: AED S-SC HA PGH CV VP JBR HH EG LK AMJ MR DL MC JMH IR-E DTP SJT AJH. Contributed reagents/materials/analysis tools: JCG TRW JBR NC HH EG LK AMJ MR DL MC JMH IR-E DTP SJT. Contributed to the writing of the manuscript: AED S-SC PGH CV JBR DTP SJT AJH.