About the Authors

Susan L. Brockmeier

susan.brockmeier@ars.usda.gov

Affiliation Virus and Prion Diseases Research Unit, National Animal Disease Center, Agricultural Research Service, USDA, Ames, Iowa, United States of America

Karen B. Register

Affiliation Ruminant Diseases and Immunology Research Unit, National Animal Disease Center, Agricultural Research Service, USDA, Ames, Iowa, United States of America

Joanna S. Kuehn

Affiliation Department of Veterinary Microbiology and Preventive Medicine, College of Veterinary Medicine, Iowa State University, Ames, Iowa, United States of America

Tracy L. Nicholson

Affiliation Virus and Prion Diseases Research Unit, National Animal Disease Center, Agricultural Research Service, USDA, Ames, Iowa, United States of America

Crystal L. Loving

Affiliation Virus and Prion Diseases Research Unit, National Animal Disease Center, Agricultural Research Service, USDA, Ames, Iowa, United States of America

Darrell O. Bayles

Affiliation Infectious Bacterial Diseases Research Unit, National Animal Disease Center, Agricultural Research Service, USDA, Ames, Iowa, United States of America

Sarah M. Shore

Affiliation Virus and Prion Diseases Research Unit, National Animal Disease Center, Agricultural Research Service, USDA, Ames, Iowa, United States of America

Gregory J. Phillips

Affiliation Department of Veterinary Microbiology and Preventive Medicine, College of Veterinary Medicine, Iowa State University, Ames, Iowa, United States of America

Competing Interests

J. S. Kuehn was not an employee of the Boehringer Ingelheim Vetmedica, Inc. (BIVI). BIVI through an informal agreement with G. J. Phillips provided money for her to be hired through Iowa State University. There are no other relevant declarations relating to employment, consultancy, patents, products in development, or marketed products, etc. And the authors agree to the following statement “This does not alter our adherence to PLOS ONE policies on sharing data and materials.” There are no restrictions on sharing of data and/or materials.

Author Contributions

Conceived and designed the experiments: SLB KBR JSK TLN CLL GJP. Performed the experiments: SLB KBR JSK TLN CLL SMS GJP. Analyzed the data: SLB KBR JSK TLN CLL DOB SMS GJP. Contributed reagents/materials/analysis tools: SLB KBR JSK TLN CLL DOB SMS GJP. Wrote the paper: SLB KBR JSK TLN CLL DOB SMS GJP.