The Role of Melanin Concentrating Hormone (MCH) in the Central Chemoreflex: A Knockdown Study by siRNA in the Lateral Hypothalamus in Rats

Ningjing Li; Eugene Nattie; Aihua Li

doi:10.1371/journal.pone.0103585

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Open Access

Peer-reviewed

Research Article

The Role of Melanin Concentrating Hormone (MCH) in the Central Chemoreflex: A Knockdown Study by siRNA in the Lateral Hypothalamus in Rats

Ningjing Li,

Affiliation Department of Physiology and Neurobiology, Geisel School of Medicine at Dartmouth, Lebanon, New Hampshire, United States of America
⨯
Eugene Nattie,

Affiliation Department of Physiology and Neurobiology, Geisel School of Medicine at Dartmouth, Lebanon, New Hampshire, United States of America
⨯
Aihua Li

* E-mail: Aihua.Li@Dartmouth.edu

Affiliation Department of Physiology and Neurobiology, Geisel School of Medicine at Dartmouth, Lebanon, New Hampshire, United States of America
⨯

The Role of Melanin Concentrating Hormone (MCH) in the Central Chemoreflex: A Knockdown Study by siRNA in the Lateral Hypothalamus in Rats

Ningjing Li,
Eugene Nattie,
Aihua Li

Published: August 1, 2014
https://doi.org/10.1371/journal.pone.0103585

About the Authors

Ningjing Li

Affiliation Department of Physiology and Neurobiology, Geisel School of Medicine at Dartmouth, Lebanon, New Hampshire, United States of America

Eugene Nattie

Affiliation Department of Physiology and Neurobiology, Geisel School of Medicine at Dartmouth, Lebanon, New Hampshire, United States of America

Aihua Li

* E-mail: Aihua.Li@Dartmouth.edu

Affiliation Department of Physiology and Neurobiology, Geisel School of Medicine at Dartmouth, Lebanon, New Hampshire, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: NL AL EN. Performed the experiments: NL. Analyzed the data: NL. Contributed reagents/materials/analysis tools: NL AL EN. Contributed to the writing of the manuscript: NL AL EN.

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Small interfering RNA
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Neurons
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Sleep
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Gene expression
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Central nervous system
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