About the Authors

Matthew B. Kilgore

Affiliation Donald Danforth Plant Science Center, St. Louis, Missouri, United States of America

Megan M. Augustin

Affiliation Donald Danforth Plant Science Center, St. Louis, Missouri, United States of America

Courtney M. Starks

Affiliation Sequoia Sciences, St Louis, Missouri, United States of America

Mark O’Neil-Johnson

Affiliation Sequoia Sciences, St Louis, Missouri, United States of America

Gregory D. May

Affiliation National Center for Genome Resources, Santa Fe, New Mexico, United States of America

John A. Crow

Affiliation National Center for Genome Resources, Santa Fe, New Mexico, United States of America

Toni M. Kutchan

tmkutchan@danforthcenter.org

Affiliation Donald Danforth Plant Science Center, St. Louis, Missouri, United States of America

Competing Interests

A provisional patent application has been filed on the norbelladine ’-Omethyltransferase gene sequence and enzyme activity reported in this manuscript. Co-authors from Sequoia Sciences are collaborators who provided NMR spectroscopic analysis of the enzymatic product. These interests will not alter the authors' adherence to PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: MBK TMK. Performed the experiments: MBK MMA CMS. Analyzed the data: MBK MMA CMS MOJ GDM JAC TMK. Contributed reagents/materials/analysis tools: MOJ GDM TMK. Contributed to the writing of the manuscript: MBK MMA CMS MOJ GDM JAC TMK.