A Population Genetic Model for the Initial Spread of Partially Resistant Malaria Parasites under Anti-Malarial Combination Therapy and Weak Intrahost Competition

Yuseob Kim; Ananias A. Escalante; Kristan A. Schneider

doi:10.1371/journal.pone.0101601

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Open Access

Peer-reviewed

Research Article

A Population Genetic Model for the Initial Spread of Partially Resistant Malaria Parasites under Anti-Malarial Combination Therapy and Weak Intrahost Competition

Yuseob Kim ,

* E-mail: yuseob@ewha.ac.kr

Affiliation Department of Life Science and Division of EcoScience, Ewha Womans University, Seoul, South Korea
⨯
Ananias A. Escalante,

Affiliation School of Life Sciences and Center for Evolutionary Medicine and Informatics at the Biodesign Institute, Arizona State University, Tempe, Arizona, United States of America
⨯
Kristan A. Schneider

Affiliation Department of Mathematics, University of Applied Sciences, Mittweida, Germany
⨯

A Population Genetic Model for the Initial Spread of Partially Resistant Malaria Parasites under Anti-Malarial Combination Therapy and Weak Intrahost Competition

Yuseob Kim,
Ananias A. Escalante,
Kristan A. Schneider

Published: July 9, 2014
https://doi.org/10.1371/journal.pone.0101601

About the Authors

Yuseob Kim

* E-mail: yuseob@ewha.ac.kr

Affiliation Department of Life Science and Division of EcoScience, Ewha Womans University, Seoul, South Korea

Ananias A. Escalante

Affiliation School of Life Sciences and Center for Evolutionary Medicine and Informatics at the Biodesign Institute, Arizona State University, Tempe, Arizona, United States of America

Kristan A. Schneider

Affiliation Department of Mathematics, University of Applied Sciences, Mittweida, Germany

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: YK KS AE. Performed the experiments: YK. Analyzed the data: YK KS. Wrote the paper: YK.

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Parasitic diseases
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Drug therapy
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Parasite evolution
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Haplotypes
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Malarial parasites
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Parasitism
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Mosquitoes
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Evolutionary genetics
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