About the Authors

Sarah L. May

Current address: Institute for Bioscience and Biotechnology Research, University of Maryland, Rockville, Maryland, United States of America

Affiliations Masonic Cancer Center, University of Minnesota, Minneapolis, Minnesota, United States of America, Department of Veterinary Clinical Sciences, College of Veterinary Medicine, University of Minnesota, St Paul, Minnesota, United States of America

Qing Zhou

Current address: Food and Drug Administration/CDER, Bethesda, Maryland, United States of America

Affiliations Masonic Cancer Center, University of Minnesota, Minneapolis, Minnesota, United States of America, Department of Pediatrics, School of Medicine, University of Minnesota, Minneapolis, Minnesota, United States of America

Mitzi Lewellen

Affiliations Masonic Cancer Center, University of Minnesota, Minneapolis, Minnesota, United States of America, Department of Veterinary Clinical Sciences, College of Veterinary Medicine, University of Minnesota, St Paul, Minnesota, United States of America

Cristan M. Carter

Affiliations Integrated Department of Immunology, School of Medicine, University of Colorado, Denver, Colorado, United States of America, University of Colorado Cancer Center, Aurora, Colorado, United States of America

David Coffey

Current address: Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America

Affiliations Integrated Department of Immunology, School of Medicine, University of Colorado, Denver, Colorado, United States of America, University of Colorado Cancer Center, Aurora, Colorado, United States of America

Steven L. Highfill

Current address: NCI/Pediatric Oncology Branch, Bethesda, Maryland, United States of America

Affiliations Masonic Cancer Center, University of Minnesota, Minneapolis, Minnesota, United States of America, Department of Pediatrics, School of Medicine, University of Minnesota, Minneapolis, Minnesota, United States of America

Christoph M. Bucher

Current address: Diagnostic Hematology, University Hospital, Basel, Switzerland

Affiliations Masonic Cancer Center, University of Minnesota, Minneapolis, Minnesota, United States of America, Department of Pediatrics, School of Medicine, University of Minnesota, Minneapolis, Minnesota, United States of America

Ilze Matise

Current address: Faculty of Veterinary Medicine, Latvia University of Agriculture, Jelgava, Latvia

Affiliations Masonic Cancer Center, University of Minnesota, Minneapolis, Minnesota, United States of America, Department of Veterinary Population Medicine, College of Veterinary Medicine, University of Minnesota, St Paul, Minnesota, United States of America

Herbert C. Morse III

Affiliation National Institute of Allergy and Infectious Diseases, NIH, Rockville, Maryland, United States of America

M. Gerard O’Sullivan

Affiliations Masonic Cancer Center, University of Minnesota, Minneapolis, Minnesota, United States of America, Department of Veterinary Population Medicine, College of Veterinary Medicine, University of Minnesota, St Paul, Minnesota, United States of America

Melissa Schutten

Current address: Genentech, South San Francisco, California, United States of America

Affiliations Masonic Cancer Center, University of Minnesota, Minneapolis, Minnesota, United States of America, Department of Veterinary Population Medicine, College of Veterinary Medicine, University of Minnesota, St Paul, Minnesota, United States of America

Charles Johnson

Current address: Abaxis Labs, Olathe, Kansas, United States of America

Affiliations Masonic Cancer Center, University of Minnesota, Minneapolis, Minnesota, United States of America, Department of Veterinary Population Medicine, College of Veterinary Medicine, University of Minnesota, St Paul, Minnesota, United States of America

Donald Bellgrau

Affiliations Integrated Department of Immunology, School of Medicine, University of Colorado, Denver, Colorado, United States of America, University of Colorado Cancer Center, Aurora, Colorado, United States of America

Bruce R. Blazar

Affiliations Masonic Cancer Center, University of Minnesota, Minneapolis, Minnesota, United States of America, Department of Pediatrics, School of Medicine, University of Minnesota, Minneapolis, Minnesota, United States of America

Jaime F. Modiano

modiano@umn.edu

Affiliations Masonic Cancer Center, University of Minnesota, Minneapolis, Minnesota, United States of America, Department of Veterinary Clinical Sciences, College of Veterinary Medicine, University of Minnesota, St Paul, Minnesota, United States of America, Integrated Department of Immunology, School of Medicine, University of Colorado, Denver, Colorado, United States of America, University of Colorado Cancer Center, Aurora, Colorado, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: JFM DB. Performed the experiments: SLM QZ CMC DC SLH CMB ML IM HCM MGOS MS CJ. Analyzed the data: SLM IM HCM MGOS DB BRB JFM. Contributed to the writing of the manuscript: SLM JFM HCM BRB DB QZ ML CMC DC SLH CMB IM MGOS MS CJ. Obtained funding support: JFM DB BRB.