Identification of a Novel Protein Complex Containing ASIC1a and GABAA Receptors and Their Interregulation

Dongbo Zhao; Nannan Ning; Zhen Lei; Hua Sun; Chuanfei Wei; Dawei Chen; Jingxin Li

doi:10.1371/journal.pone.0099735

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Open Access

Peer-reviewed

Research Article

Identification of a Novel Protein Complex Containing ASIC1a and GABA_A Receptors and Their Interregulation

Dongbo Zhao ,

Contributed equally to this work with: Dongbo Zhao, Nannan Ning

Affiliation Department of Thoracic Surgery, Shandong Cancer Hospital and Institute, Jinan, China
⨯
Nannan Ning ,

Contributed equally to this work with: Dongbo Zhao, Nannan Ning

Affiliation Department of Physiology, School of Medicine, Shandong University, Jinan, China
⨯
Zhen Lei,

Affiliation Department of Anesthesiology, Qilu Hospital, Shandong University, Jinan, China
⨯
Hua Sun,

Affiliation Department of Thoracic Surgery, Shandong Cancer Hospital and Institute, Jinan, China
⨯
Chuanfei Wei,

Affiliation Department of Physiology, School of Medicine, Shandong University, Jinan, China
⨯
Dawei Chen,

Affiliation Department of Physiology, School of Medicine, Shandong University, Jinan, China
⨯
Jingxin Li

Affiliation Department of Physiology, School of Medicine, Shandong University, Jinan, China
⨯

Identification of a Novel Protein Complex Containing ASIC1a and GABA_A Receptors and Their Interregulation

Dongbo Zhao,
Nannan Ning,
Zhen Lei,
Hua Sun,
Chuanfei Wei,
Dawei Chen,
Jingxin Li

Published: June 12, 2014
https://doi.org/10.1371/journal.pone.0099735

About the Authors

Dongbo Zhao

Contributed equally to this work with: Dongbo Zhao, Nannan Ning

Affiliation Department of Thoracic Surgery, Shandong Cancer Hospital and Institute, Jinan, China

Nannan Ning

Contributed equally to this work with: Dongbo Zhao, Nannan Ning

Affiliation Department of Physiology, School of Medicine, Shandong University, Jinan, China

Zhen Lei

Affiliation Department of Anesthesiology, Qilu Hospital, Shandong University, Jinan, China

Hua Sun

Affiliation Department of Thoracic Surgery, Shandong Cancer Hospital and Institute, Jinan, China

Chuanfei Wei

Affiliation Department of Physiology, School of Medicine, Shandong University, Jinan, China

Dawei Chen

Affiliation Department of Physiology, School of Medicine, Shandong University, Jinan, China

Jingxin Li

Affiliation Department of Physiology, School of Medicine, Shandong University, Jinan, China

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: JL. Performed the experiments: DZ NN ZL HS CW DC. Analyzed the data: DZ NN ZL JL. Contributed reagents/materials/analysis tools: CW DC. Wrote the paper: JL.

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Neurons
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Transfection
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Co-immunoprecipitation
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Gamma-aminobutyric acid
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Immunoprecipitation
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Protons
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Protein complexes
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Ligand-gated ion channels
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