About the Authors

Matthew L. Brown

Affiliations Center for Musculoskeletal Research, University of Rochester Medical Center, Rochester, New York, United States of America, School of Medicine and Dentistry, University of Rochester Medical Center, Rochester, New York, United States of America

Kiminori Yukata

Affiliation Center for Musculoskeletal Research, University of Rochester Medical Center, Rochester, New York, United States of America

Christopher W. Farnsworth

Affiliations Center for Musculoskeletal Research, University of Rochester Medical Center, Rochester, New York, United States of America, Department of Pathology and Laboratory Medicine, University of Rochester Medical Center, Rochester, New York, United States of America

Ding-Geng Chen

Affiliations Center for Musculoskeletal Research, University of Rochester Medical Center, Rochester, New York, United States of America, Department of Biostatistics and Computational Biology, University of Rochester Medical Center, Rochester, New York, United States of America

Hani Awad

Affiliations Center for Musculoskeletal Research, University of Rochester Medical Center, Rochester, New York, United States of America, Department of Orthopaedics and Rehabilitation, University of Rochester Medical Center, Rochester, New York, United States of America, Department of Biomechanical Engineering, University of Rochester, Rochester, New York, United States of America

Matthew J. Hilton

Affiliations Center for Musculoskeletal Research, University of Rochester Medical Center, Rochester, New York, United States of America, Department of Orthopaedics and Rehabilitation, University of Rochester Medical Center, Rochester, New York, United States of America

Regis J. O'Keefe

Affiliations Center for Musculoskeletal Research, University of Rochester Medical Center, Rochester, New York, United States of America, Department of Orthopaedics and Rehabilitation, University of Rochester Medical Center, Rochester, New York, United States of America

Lianping Xing

Affiliations Center for Musculoskeletal Research, University of Rochester Medical Center, Rochester, New York, United States of America, Department of Pathology and Laboratory Medicine, University of Rochester Medical Center, Rochester, New York, United States of America

Robert A. Mooney

Affiliations Center for Musculoskeletal Research, University of Rochester Medical Center, Rochester, New York, United States of America, Department of Pathology and Laboratory Medicine, University of Rochester Medical Center, Rochester, New York, United States of America

Michael J. Zuscik

michael_zuscik@urmc.rochester.edu

Affiliations Center for Musculoskeletal Research, University of Rochester Medical Center, Rochester, New York, United States of America, Department of Orthopaedics and Rehabilitation, University of Rochester Medical Center, Rochester, New York, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: MLB KY HA RJO LX RAM MJZ. Performed the experiments: MLB KY CWF RAM. Analyzed the data: MLB KY CWF DGC MJH LX RAM MJZ. Contributed reagents/materials/analysis tools: HA MJH RJO LX RAM MJZ. Wrote the paper: MLB RAM MJZ.