About the Authors

Adam J. Pritchard

Affiliation Drug Development, School of Medicine, Trinity College Dublin, Dublin, Ireland

Anis K. Mir

Affiliation Autoimmunity, Transplantation and Inflammatory Disease, Novartis Institutes for BioMedical Research, Novartis Pharma AG, Basel, Switzerland

Kumlesh K. Dev

devk@tcd.ie

Affiliation Drug Development, School of Medicine, Trinity College Dublin, Dublin, Ireland

Competing Interests

The authors have read the journal's policy and have the following conflicts: AKM is an employee of Novartis Pharma Basel. This does not alter the authors' adherence to PLOS ONE policies on sharing data and materials under relevant material transfer agreements.

Author Contributions

Conceived and designed the experiments: AKM KKD. Performed the experiments: AJP. Analyzed the data: AJP AKM KKD. Contributed reagents/materials/analysis tools: AKM KKD. Wrote the paper: AJP AKM KKD.