About the Authors

Suman Kanungo

Affiliation Department of Epidemiology, National Institute of Cholera & Enteric Diseases, Kolkata, West Bengal, India

Bandana Sen

Affiliation Society for Applied Studies, Kolkata, West Bengal, India

Thandavarayan Ramamurthy

Affiliation Department of Microbiology, National Institute of Cholera & Enteric Diseases, Kolkata, West Bengal, India

Dipika Sur

Affiliation Department of Epidemiology, National Institute of Cholera & Enteric Diseases, Kolkata, West Bengal, India

Byomkesh Manna

Affiliation Department of Epidemiology, National Institute of Cholera & Enteric Diseases, Kolkata, West Bengal, India

Gururaja P. Pazhani

Affiliation Department of Microbiology, National Institute of Cholera & Enteric Diseases, Kolkata, West Bengal, India

Goutam Chowdhury

Affiliation Department of Microbiology, National Institute of Cholera & Enteric Diseases, Kolkata, West Bengal, India

Puja Jhunjhunwala

Affiliation Department of Microbiology, National Institute of Cholera & Enteric Diseases, Kolkata, West Bengal, India

Ranjan K. Nandy

Affiliation Department of Microbiology, National Institute of Cholera & Enteric Diseases, Kolkata, West Bengal, India

Hemanta Koley

Affiliation Department of Microbiology, National Institute of Cholera & Enteric Diseases, Kolkata, West Bengal, India

Mihir Kumar Bhattacharya

Affiliation Department of Epidemiology, National Institute of Cholera & Enteric Diseases, Kolkata, West Bengal, India

Sanjay Gupta

Affiliation Catalyst Clinical Services Pvt. Ltd., Delhi, India

Gaurav Goel

Affiliation Catalyst Clinical Services Pvt. Ltd., Delhi, India

Bindu Dey

Affiliation Department of Biotechnology, Ministry of Science and Technology, New Delhi, India

Thungapathra M

Affiliation Institute of Post Graduate Medicine and Research, Chandigarh, India

G. Balakrish Nair

Affiliation Translational Health Science and Technology Institute, Gurgaon, Haryana, India

Amit Ghosh

Affiliation Department of Microbiology, National Institute of Cholera & Enteric Diseases, Kolkata, West Bengal, India

Dilip Mahalanabis

sas_kolkata@vsnl.net

Affiliation Society for Applied Studies, Kolkata, West Bengal, India

Competing Interests

The Department of Biotechnology of the Ministry of Science and Technology (DBT) contracted Shantha Biotechnics Private Limited, Hyderabad, India to develop the vaccine into a clinical product (IP) for the present study. None of the authors are affiliated with Shantha Biotechnics Private Limited. Sanjay Gupta and Gaurav Goel from the Catalyst Clinical Services Pvt. Ltd were contracted by DBT for monitoring and overseeing the trial to assist in the fulfillment of Regulatory Requirements for an investigational product evaluation. DBT paid the Catalyst Clinical Services Pvt. Ltd. for their services. None of the authors have had any competing interest, financial or otherwise, with Catalyst Clinical Services Pvt. Ltd. Sanjay Gupta and Gaurav Goel were not involved in data entry, data analysis or interpretation. Dr. Bindu Dey is a staff member of DBT and was involved in coordinating the research project. There are no patents, products in development or marketed products to declare. This does not alter the authors' adherence to PLOS ONE policies or sharing data and materials.

Author Contributions

Conceived and designed the experiments: DM SK DS TR GBN AG. Performed the experiments: DM SK BS MKB. Analyzed the data: DM BS BM. Contributed reagents/materials/analysis tools: TR GPP GC PJ RKN HK TM GBN AG. Wrote the paper: DM SK BS TR. Contracted research organization responsible for documentation and regular monitoring of the project: SG GG. Sponsor, responsible for documentation and regular monitoring of the project: BD.