About the Authors

Yoshihisa Mizukami

Affiliation Division of Regenerative Medicine, Center for Molecular Medicine, Jichi Medical University, Tochigi, Japan

Tomoyuki Abe

Affiliations Division of Regenerative Medicine, Center for Molecular Medicine, Jichi Medical University, Tochigi, Japan, Center for Development of Advanced Medical Technology, Jichi Medical University, Tochigi, Japan

Hiroaki Shibata

Affiliation Tsukuba Primate Research Center, National Institute of Biomedical Innovation, Ibaraki, Japan

Yukitoshi Makimura

Affiliation Center for Development of Advanced Medical Technology, Jichi Medical University, Tochigi, Japan

Shuh-hei Fujishiro

Affiliation Division of Regenerative Medicine, Center for Molecular Medicine, Jichi Medical University, Tochigi, Japan

Kimihide Yanase

Affiliation Division of Regenerative Medicine, Center for Molecular Medicine, Jichi Medical University, Tochigi, Japan

Shuji Hishikawa

Affiliation Center for Development of Advanced Medical Technology, Jichi Medical University, Tochigi, Japan

Eiji Kobayashi

Affiliation Center for Development of Advanced Medical Technology, Jichi Medical University, Tochigi, Japan

Yutaka Hanazono

hanazono@jichi.ac.jp

Affiliations Division of Regenerative Medicine, Center for Molecular Medicine, Jichi Medical University, Tochigi, Japan, Center for Development of Advanced Medical Technology, Jichi Medical University, Tochigi, Japan, CREST, Japan Science and Technology Agency, Tokyo, Japan

Competing Interests

Prof. Eiji Kobayashi is a chief scientific advisor; however, this does not alter the authors' adherence to all PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: Y. Mizukami TA YH. Performed the experiments: Y. Mizukami TA HS Y. Makimura KY SH EK. Analyzed the data: Y. Mizukami TA YH. Contributed reagents/materials/analysis tools: HS SF. Wrote the paper: Y. Mizukami YH.