About the Authors

Erika Parkinson

epp@soton.ac.uk

Affiliations Centre for Biological Sciences, University of Southampton, Southampton, United Kingdom, Centre for Proteomic Research, Institute for Life Sciences, University of Southampton, Southampton, United Kingdom

Paul Skipp

Affiliations Centre for Biological Sciences, University of Southampton, Southampton, United Kingdom, Centre for Proteomic Research, Institute for Life Sciences, University of Southampton, Southampton, United Kingdom

Maja Aleksic

Affiliation Safety & Environmental Assurance Centre, Unilever, Colworth Science Park, Sharnbrook, United Kingdom

Andrew Garrow

Affiliation Safety & Environmental Assurance Centre, Unilever, Colworth Science Park, Sharnbrook, United Kingdom

Tony Dadd

Affiliation Unilever Clinicals, Unilever Research, Colworth Science Park, Sharnbrook, United Kingdom

Michael Hughes

Affiliation Safety & Environmental Assurance Centre, Unilever, Colworth Science Park, Sharnbrook, United Kingdom

Geraldine Clough

Affiliation Institute for Developmental Sciences, School of Medicine, University of Southampton, Southampton, United Kingdom

C. David O′Connor

Affiliations Centre for Biological Sciences, University of Southampton, Southampton, United Kingdom, Centre for Proteomic Research, Institute for Life Sciences, University of Southampton, Southampton, United Kingdom

Competing Interests

The authors have the following interests. This study was funded by SEAC, Unilever plc. study KOM060136. MA, AG, TD and MW were employees of Unilever and the salary of EP was funded by Unilever at the time of the study. There are no patents, products in development or marketed products to declare. This does not alter the authors' adherence to all the PLOS ONE policies on sharing data and materials, as detailed online in the guide for authors.

Author Contributions

Conceived and designed the experiments: EP PS MA GC CDO'C. Performed the experiments: EP PS. Analyzed the data: EP AG TD MH. Wrote the paper: EP PS MA AG TD MH GC CD'OC.