About the Authors
- Sawako Moriwaki
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Contributed equally to this work with: Sawako Moriwaki, Keiko Suzuki
Affiliations Laboratory of Genomics and Proteomics, National Center for Geriatrics and Gerontology (NCGG), Aichi, Japan, Biobank Omics Unit, National Center for Geriatrics and Gerontology (NCGG), Aichi, Japan
- Keiko Suzuki
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Contributed equally to this work with: Sawako Moriwaki, Keiko Suzuki
Affiliation Department of Pharmacology, School of Dentistry, Showa University, Tokyo, Japan
- Masashi Muramatsu
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Current address: Department of Cancer Genetics, Roswell Park Cancer Institute, Elm and Carlton Streets, Buffalo, New York, United States of America
Affiliation Laboratory of Genomics and Proteomics, National Center for Geriatrics and Gerontology (NCGG), Aichi, Japan
- Atsushi Nomura
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Affiliation Nihon Seiyaku Kogyo, Co., Ltd., Aichi, Japan
- Fumihide Inoue
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Affiliation Nihon Seiyaku Kogyo, Co., Ltd., Aichi, Japan
- Takeshi Into
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Affiliation Department of Oral Bacteriology, Division of Oral Infections and Health Sciences, Asahi University School of Dentistry, Gifu, Japan
- Yuji Yoshiko
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Affiliation Department of Oral Growth and Developmental Biology, Hiroshima University Graduate School of Biomedical Sciences, Hiroshima, Japan
- Shumpei Niida
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* E-mail: sniida@ncgg.go.jp
Affiliations Laboratory of Genomics and Proteomics, National Center for Geriatrics and Gerontology (NCGG), Aichi, Japan, Biobank Omics Unit, National Center for Geriatrics and Gerontology (NCGG), Aichi, Japan
Competing Interests
AN and FI are employees of Nihon Seiyaku Kogyo Co., Ltd. Tama Biochemical Co. Ltd., who donated experimental material Cassis-extract-35, also declared that no competing interests exist. This does not alter adherence to all PLOS ONE policies on sharing data and materials.
Author Contributions
Conceived and designed the experiments: SN. Performed the experiments: SM KS MM YY. Analyzed the data: KS TI YY. Contributed reagents/materials/analysis tools: AN FI. Wrote the paper: SN.