About the Authors

Dante Rotili

Affiliation Dipartimento di Chimica e Tecnologie del Farmaco, Sapienza Università di Roma, Roma, IT

Domenico Tarantino

Affiliation Dipartimento di Chimica e Tecnologie del Farmaco, Sapienza Università di Roma, Roma, IT

Biagina Marrocco

Affiliation Dipartimento di Chimica e Tecnologie del Farmaco, Sapienza Università di Roma, Roma, IT

Christina Gros

Affiliation USR3388 CNRS-Pierre Fabre ETaC, CRDPF, Toulouse, France

Véronique Masson

Affiliation USR3388 CNRS-Pierre Fabre ETaC, CRDPF, Toulouse, France

Valérie Poughon

Affiliation USR3388 CNRS-Pierre Fabre ETaC, CRDPF, Toulouse, France

Fréderic Ausseil

Affiliation USR3388 CNRS-Pierre Fabre ETaC, CRDPF, Toulouse, France

Yanqi Chang

Affiliation Department of Biochemistry, Emory University School of Medicine, Atlanta, Georgia, United States of America

Donatella Labella

Affiliation Dipartimento di Chimica e Tecnologie del Farmaco, Sapienza Università di Roma, Roma, IT

Sandro Cosconati

Affiliation DiSTABiF, Seconda Università di Napoli, Caserta, Italy

Salvatore Di Maro

Affiliation Dipartimento di Farmacia, Università di Napoli “Federico II”, Napoli, IT

Ettore Novellino

Affiliation Dipartimento di Farmacia, Università di Napoli “Federico II”, Napoli, IT

Michael Schnekenburger

Affiliation Laboratoire de Biologie Moléculaire et Cellulaire du Cancer (LBMCC), Luxembourg, Luxembourg

Cindy Grandjenette

Affiliation Laboratoire de Biologie Moléculaire et Cellulaire du Cancer (LBMCC), Luxembourg, Luxembourg

Celine Bouvy

Affiliation Laboratoire de Biologie Moléculaire et Cellulaire du Cancer (LBMCC), Luxembourg, Luxembourg

Marc Diederich

Affiliations Laboratoire de Biologie Moléculaire et Cellulaire du Cancer (LBMCC), Luxembourg, Luxembourg, Department of Pharmacy, College of Pharmacy, Seoul National University, Seoul, Korea

Xiaodong Cheng

Affiliation Department of Biochemistry, Emory University School of Medicine, Atlanta, Georgia, United States of America

Paola B. Arimondo

Affiliation USR3388 CNRS-Pierre Fabre ETaC, CRDPF, Toulouse, France

Antonello Mai

antonello.mai@uniroma1.it

Affiliations Dipartimento di Chimica e Tecnologie del Farmaco, Sapienza Università di Roma, Roma, IT, Istituto Pasteur-Fondazione Cenci Bolognetti, Sapienza Università di Roma, Roma, IT

Competing Interests

This study was partly supported through a postdoctoral grant from FNRS Télévie Luxembourg. There are no patents, products in development or marketed products to declare. This does not alter the authors' adherence to all the PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: SC EN MS MD XC PBA AM. Performed the experiments: DR DT BM C. Gros VM VP YC DL SC SDM C. Grandjenette CB. Analyzed the data: DR C. Gros FA SC MS MD XC PBA AM. Contributed reagents/materials/analysis tools: DR MD XC PBA AM. Wrote the paper: DR SC MS MD XC PBA AM.