About the Authors

Shamsul Mohd Zain

soulz712@gmail.com (SMZ); ros@ummc.edu.my (RM)

Affiliations The Pharmacogenomics Laboratory, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia, Department of Pharmacology, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia

Rosmawati Mohamed

soulz712@gmail.com (SMZ); ros@ummc.edu.my (RM)

Affiliation Department of Medicine, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia

David N. Cooper

Affiliation Institute of Medical Genetics, School of Medicine, Cardiff University, Cardiff, United Kingdom

Rozaimi Razali

Affiliation Sengenics Sdn Bhd, High Impact Reseach Building, University of Malaya, Kuala Lumpur, Malaysia

Sanjay Rampal

Affiliation Julius Centre University of Malaya, Department of Social and Preventive Medicine, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia

Sanjiv Mahadeva

Affiliation Department of Medicine, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia

Wah-Kheong Chan

Affiliation Department of Medicine, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia

Arif Anwar

Affiliation Sengenics Sdn Bhd, High Impact Reseach Building, University of Malaya, Kuala Lumpur, Malaysia

Nurul Shielawati Mohamed Rosli

Affiliation Sengenics Sdn Bhd, High Impact Reseach Building, University of Malaya, Kuala Lumpur, Malaysia

Anis Shafina Mahfudz

Affiliation Medical Imaging Unit, Faculty of Medicine, University of Technology MARA, Sungai Buloh Campus, Selangor, Malaysia

Phaik-Leng Cheah

Affiliation Department of Pathology, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia

Roma Choudhury Basu

Affiliation Clinical Investigation Centre, University Malaya Medical Centre, Kuala Lumpur, Malaysia

Zahurin Mohamed

Affiliations The Pharmacogenomics Laboratory, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia, Department of Pharmacology, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia

Competing Interests

Sengenics Sdn Bhd is not a funder and has no competing interest and financial disclosure along with any other relevant declarations relating to employment, consultancy, patents, products in development or marketed products. This does not alter the authors' adherence to PLOS ONE policies on sharing data and materials. The authors certify that the submission is an original work and is not under review at any other journals.

Author Contributions

Conceived and designed the experiments: SMZ RM ZM. Performed the experiments: SMZ NSMR. Analyzed the data: SMZ RR SR. Contributed reagents/materials/analysis tools: SM WKC RCB ASM PLC. Wrote the paper: SMZ. Interpretation of data: SMZ RR AA DNC. Drafting the article or revising it critically for important intellectual content: SMZ DNC RM ZM.