About the Authors

Se Won Oh

Affiliation Department of Internal Medicine, Inje University College of Medicine, Goyang City, Gyeonggi-do, Korea

Sejoong Kim

Affiliation Department of Internal Medicine, Seoul National University Bundang Hopsital, Seong-Nam, Korea

Ki Young Na

Affiliations Department of Internal Medicine, Seoul National University Bundang Hopsital, Seong-Nam, Korea, Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea

Ki Woong Kim

Affiliation Department of Psychiatry, Seoul National University College of Medicine, Seoul, Korea

Dong-Wan Chae

Affiliations Department of Internal Medicine, Seoul National University Bundang Hopsital, Seong-Nam, Korea, Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea

Ho Jun Chin

mednep@snubh.org

Affiliations Department of Internal Medicine, Seoul National University Bundang Hopsital, Seong-Nam, Korea, Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea

Competing Interests

This study was supported by Pfizer Global Pharmaceuticals. There are no patents, products in development or marketed products to declare. This does not alter the authors’ adherence to all the PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: HJC SWO SK KYN KWK DWC. Performed the experiments: HJC SWO. Analyzed the data: HJC SWO. Contributed reagents/materials/analysis tools: HJC SWO. Wrote the paper: HJC SWO. Revised the paper for important intellectual content and have seen and approved the final version: SWO SK KYN KWK DWC HJC.