Thyroid Hormone Regulation of Gene Expression in Primary Cerebrocortical Cells: Role of Thyroid Hormone Receptor Subtypes and Interactions with Retinoic Acid and Glucocorticoids

Pilar Gil-Ibáñez; Juan Bernal; Beatriz Morte

doi:10.1371/journal.pone.0091692

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Peer-reviewed

Research Article

Thyroid Hormone Regulation of Gene Expression in Primary Cerebrocortical Cells: Role of Thyroid Hormone Receptor Subtypes and Interactions with Retinoic Acid and Glucocorticoids

Pilar Gil-Ibáñez,

Affiliations Instituto de Investigaciones Biomédicas, Consejo Superior de Investigaciones Científicas (CSIC), Madrid, Spain, Universidad Autónoma de Madrid (UAM), Madrid, Spain, Center for Biomedical Research On Rare Diseases (Ciberer), Instituto de Salud Carlos III, Madrid, Spain
⨯
Juan Bernal ,

* E-mail: jbernal@iib.uam.es (JB); bmorte@iib.uam.es (BM)

Affiliations Instituto de Investigaciones Biomédicas, Consejo Superior de Investigaciones Científicas (CSIC), Madrid, Spain, Universidad Autónoma de Madrid (UAM), Madrid, Spain, Center for Biomedical Research On Rare Diseases (Ciberer), Instituto de Salud Carlos III, Madrid, Spain
⨯
Beatriz Morte

* E-mail: jbernal@iib.uam.es (JB); bmorte@iib.uam.es (BM)

Affiliations Instituto de Investigaciones Biomédicas, Consejo Superior de Investigaciones Científicas (CSIC), Madrid, Spain, Universidad Autónoma de Madrid (UAM), Madrid, Spain, Center for Biomedical Research On Rare Diseases (Ciberer), Instituto de Salud Carlos III, Madrid, Spain
⨯

Thyroid Hormone Regulation of Gene Expression in Primary Cerebrocortical Cells: Role of Thyroid Hormone Receptor Subtypes and Interactions with Retinoic Acid and Glucocorticoids

Pilar Gil-Ibáñez,
Juan Bernal,
Beatriz Morte

Published: March 11, 2014
https://doi.org/10.1371/journal.pone.0091692

About the Authors

Pilar Gil-Ibáñez

Affiliations Instituto de Investigaciones Biomédicas, Consejo Superior de Investigaciones Científicas (CSIC), Madrid, Spain, Universidad Autónoma de Madrid (UAM), Madrid, Spain, Center for Biomedical Research On Rare Diseases (Ciberer), Instituto de Salud Carlos III, Madrid, Spain

Juan Bernal

* E-mail: jbernal@iib.uam.es (JB); bmorte@iib.uam.es (BM)

Beatriz Morte

* E-mail: jbernal@iib.uam.es (JB); bmorte@iib.uam.es (BM)

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: PG-I JB BM. Performed the experiments: PG-I. Analyzed the data: PG-I JB BM. Wrote the paper: JB BM.

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Gene expression
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Thyroid hormones
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Gene regulation
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Neurons
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Retinoic acid
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Transcriptional control
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Hypothyroidism
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Astrocytes
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