About the Authors

Vatshalan Santhirapala

Affiliations Imperial College School of Medicine, Imperial College, London, United Kingdom, National Heart and Lung Institute (NHLI) Cardiovascular Science, Imperial College, London, United Kingdom, Respiratory Medicine, Hammersmith Hospital, Imperial College Healthcare NHS Trust, London, United Kingdom

Louisa C. Williams

Affiliation Respiratory Medicine, Hammersmith Hospital, Imperial College Healthcare NHS Trust, London, United Kingdom

Hannah C. Tighe

Affiliation Respiratory Medicine, Hammersmith Hospital, Imperial College Healthcare NHS Trust, London, United Kingdom

James E. Jackson

Affiliation Department of Imaging, Hammersmith Hospital, Imperial College Healthcare NHS Trust, London, United Kingdom

Claire L. Shovlin

c.shovlin@imperial.ac.uk

Affiliations National Heart and Lung Institute (NHLI) Cardiovascular Science, Imperial College, London, United Kingdom, Respiratory Medicine, Hammersmith Hospital, Imperial College Healthcare NHS Trust, London, United Kingdom

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: VS CLS. Performed the experiments: LCW HT JEJ CLS. Analyzed the data: VS CLS. Contributed reagents/materials/analysis tools: LCW HCT JEJ CLS. Wrote the paper: CLS. Generated the database: VS. Assigned exercise tolerance grades: VS CLS. Performed pulmonary function measurements: LCW HCT. Advised on oxygen guidelines: LCW HCT. Performed embolisations and associated measurements: JEJ. Reviewed all patients: CLS. Performed statistical analyses presented: CLS. Generated the figures: CLS. Reviewed and approved the final article: VS LCW HT JEJ CLS. Guarantor of the data: CLS.