About the Authors

Mingyu Liu

Grant.walkup@astrazeneca.com (GKW); Mingyu-mandy.liu@astrazeneca.com (ML)

Affiliation Biology Department, Infection Innovative Medicines, AstraZeneca R&D Boston, Waltham, Massachusetts, United States of America

Christina Blinn

Affiliation Biology Department, Infection Innovative Medicines, AstraZeneca R&D Boston, Waltham, Massachusetts, United States of America

Sarah M. McLeod

Affiliation Biology Department, Infection Innovative Medicines, AstraZeneca R&D Boston, Waltham, Massachusetts, United States of America

John W. Wiseman

Affiliation RAD-Transgenics, Discovery Sciences, AstraZeneca R&D Mölndal, Mölndal, Sweden

Joseph V. Newman

Affiliation Biology Department, Infection Innovative Medicines, AstraZeneca R&D Boston, Waltham, Massachusetts, United States of America

Stewart L. Fisher

Affiliation Biology Department, Infection Innovative Medicines, AstraZeneca R&D Boston, Waltham, Massachusetts, United States of America

Grant K. Walkup

Grant.walkup@astrazeneca.com (GKW); Mingyu-mandy.liu@astrazeneca.com (ML)

Affiliation Biology Department, Infection Innovative Medicines, AstraZeneca R&D Boston, Waltham, Massachusetts, United States of America

Competing Interests

All authors declare the competing financial interest of employment by AstraZeneca. In addition, authors SMM, JWW, JVN, SLF, and GKW own stock and/or stock options of AstraZeneca. However, this statement does not alter the authors' adherence to PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: ML SMM JVN SLF GKW. Performed the experiments: ML CB JWW SMM. Analyzed the data: ML GKW. Wrote the paper: ML SMM SLF GKW.