About the Authors
- Walid Nachar
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Affiliation Montreal Heart Institute and Université de Montréal, Montreal, Quebec, Canada
- David Busseuil
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Affiliation Montreal Heart Institute and Université de Montréal, Montreal, Quebec, Canada
- Yanfen Shi
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Affiliation Montreal Heart Institute and Université de Montréal, Montreal, Quebec, Canada
- Teodora Mihalache-Avram
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Affiliation Montreal Heart Institute and Université de Montréal, Montreal, Quebec, Canada
- Mélanie Mecteau
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Affiliation Montreal Heart Institute and Université de Montréal, Montreal, Quebec, Canada
- Eric Rhéaume
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Affiliations Montreal Heart Institute and Université de Montréal, Montreal, Quebec, Canada, Department of Medicine, Université de Montréal, Montreal, Quebec, Canada
- Jean-Claude Tardif
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* E-mail: jean-claude.tardif@icm-mhi.org
Affiliations Montreal Heart Institute and Université de Montréal, Montreal, Quebec, Canada, Department of Medicine, Université de Montréal, Montreal, Quebec, Canada
Competing Interests
The authors have the following interests: The following patents on the theme of HDL and both aortic valve stenosis and diastolic dysfunction were submitted by the Montreal Heart Institute and Drs. Tardif, Rhéaume and Busseuil are mentioned as authors. WO/2010/083611A1 “Method for the prevention and treatment of diastolic dysfunction employing an apolipoproteinA1 (APOA1) mimetic peptide/phospholipid complex”. US20130197226 /Pharmaceutical compositions for the treatment of left ventricular diastolic dysfunction comprising an apolipoprotein peptide/phospholipid complex”. US20090186808 “Method and compound for the treatment of valvular disease”. These patents do not cover the development of a diastolic dysfunction in a rabbit model, nor the use or selection of housekeeping genes. There are no further patents, products in development or marketed products to declare. This does not alter the authors' adherence to all the PLOS ONE policies on sharing data and materials.
Author Contributions
Conceived and designed the experiments: WN DB ER JCT. Performed the experiments: WN DB YS TMA MM. Analyzed the data: WN DB YS ER JCT. Contributed reagents/materials/analysis tools: JCT. Wrote the paper: WN DB ER JCT.