About the Authors

Rossana Domenis

Contributed equally to this work with: Rossana Domenis, Natascha Bergamin

Affiliation Department of Medical and Biological Sciences, University of Udine, Udine, Italy

Natascha Bergamin

Contributed equally to this work with: Rossana Domenis, Natascha Bergamin

Affiliation Department of Medical and Biological Sciences, University of Udine, Udine, Italy

Giuseppe Gianfranceschi

Affiliation Department of Medical and Biological Sciences, University of Udine, Udine, Italy

Carlo Vascotto

Affiliation Department of Medical and Biological Sciences, University of Udine, Udine, Italy

Milena Romanello

Affiliation Department of Medical and Biological Sciences, University of Udine, Udine, Italy

Silvia Rigo

Affiliation Department of Medical and Biological Sciences, University of Udine, Udine, Italy

Giovanna Vagnarelli

Affiliation Department of Medical and Biological Sciences, University of Udine, Udine, Italy

Massimo Faggiani

Affiliation Department of Medical and Biological Sciences, University of Udine, Udine, Italy

Piercamillo Parodi

Affiliation Department of Experimental and Clinical Medical Sciences, University of Udine, Udine, Italy

Mark R. Kelley

Affiliation Department of Pediatrics (Section of Hematology/Oncology), Herman B. Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis, Indiana, United States of America

Carlo Alberto Beltrami

Affiliation Department of Medical and Biological Sciences, University of Udine, Udine, Italy

Daniela Cesselli

Affiliation Department of Medical and Biological Sciences, University of Udine, Udine, Italy

Gianluca Tell

gianluca.tell@uniud.it (GT); antonio.beltrami@uniud.it (APB)

Affiliation Department of Medical and Biological Sciences, University of Udine, Udine, Italy

Antonio Paolo Beltrami

gianluca.tell@uniud.it (GT); antonio.beltrami@uniud.it (APB)

Affiliation Department of Medical and Biological Sciences, University of Udine, Udine, Italy

Competing Interests

The authors have read the journal’s policy and declare that they have no conflict of interest, with the exception of Dr. Mark R. Kelley, who is the Chief Scientific Founder and consultant for ApeX Therapeutics, a company that has licensed IP from his work. Dr. Beltrami is a PLoS ONE Editorial Board member, but this does not alter the authors’ adherence to all the PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: DC GT APB. Performed the experiments: RD NB GG CV MR GV MF SR. Analyzed the data: RD NB CV MR DC GT APB. Contributed reagents/materials/analysis tools: MRK CAB PP. Wrote the paper: DC APB GT CAB.