About the Authors

Yong Cheng

Affiliation Department of Biological Sciences, Center for Rare and Neglected Diseases and Eck Institute for Global Health, University of Notre Dame, Notre Dame, Indiana, United States of America

Garrett C. Moraski

Affiliation Department of Chemistry and Biochemistry, University of Notre Dame, Notre Dame, Indiana, United States of America

Jeffrey Cramer

Affiliation Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, Indiana, United States of America

Marvin J. Miller

Affiliation Department of Chemistry and Biochemistry, University of Notre Dame, Notre Dame, Indiana, United States of America

Jeffrey S. Schorey

schorey.1@nd.edu

Affiliation Department of Biological Sciences, Center for Rare and Neglected Diseases and Eck Institute for Global Health, University of Notre Dame, Notre Dame, Indiana, United States of America

Competing Interests

The authors have the following interests. This study was partly funded by Hsiri Therapeutics, LLC. Jeffrey Cramer is employed by Eli Lilly and Company. There are no patents, products in development or marketed products to declare. This does not alter the authors’ adherence to all the PLOS ONE policies on sharing data and materials, as detailed online in the guide for authors.

Author Contributions

Conceived and designed the experiments: YC JSS. Performed the experiments: YC JC. Analyzed the data: YC GCM JC MJM JSS. Contributed reagents/materials/analysis tools: GCM JC MJM. Wrote the paper: YC JSS.