About the Authors

Jieqiang Zhu

Affiliation Pharmaceutical Informatics Institute, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, China

Xiaohui Fan

fanxh@zju.edu.cn (XF); rajiv.agarwal@fda.hhs.gov (RA); weida.tong@fda.hhs.gov (WT)

Affiliation Pharmaceutical Informatics Institute, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, China

Yiyu Cheng

Affiliation Pharmaceutical Informatics Institute, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, China

Rajiv Agarwal

fanxh@zju.edu.cn (XF); rajiv.agarwal@fda.hhs.gov (RA); weida.tong@fda.hhs.gov (WT)

Affiliation Office of New Drug Quality Assessment, Center for Drug Evaluation and Research (CDER), US Food and Drug Administration, Silver Spring, Maryland, United States of America

Christine M. V. Moore

Affiliation Office of New Drug Quality Assessment, Center for Drug Evaluation and Research (CDER), US Food and Drug Administration, Silver Spring, Maryland, United States of America

Shaw T. Chen

Affiliation Office of New Drugs, Center for Drug Evaluation and Research (CDER), US Food and Drug Administration, Silver Spring, Maryland, United States of America

Weida Tong

fanxh@zju.edu.cn (XF); rajiv.agarwal@fda.hhs.gov (RA); weida.tong@fda.hhs.gov (WT)

Affiliation National Center for Toxicological Research (NCTR), US Food and Drug Administration, Jefferson, Arkansas, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: XF YC RA CM SC WT. Performed the experiments: JZ XF. Analyzed the data: JZ XF RA WT. Contributed reagents/materials/analysis tools: XF YC WT. Wrote the paper: JZ XF YC RA CM SC WT.