About the Authors
- Mitsuko Kawano
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Affiliation Department of Immunobiology, Institute of Development, Aging and Cancer, Tohoku University, Aoba-ku, Sendai, Miyagi, Japan
- Masafumi Nakayama
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Affiliation Department of Immunobiology, Institute of Development, Aging and Cancer, Tohoku University, Aoba-ku, Sendai, Miyagi, Japan
- Yusuke Aoshima
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Affiliations Department of Immunobiology, Institute of Development, Aging and Cancer, Tohoku University, Aoba-ku, Sendai, Miyagi, Japan, Department of Materials Processing, Graduate School of Engineering, Tohoku University, Aramakiaza, Aoba-ku, Sendai, Miyagi, Japan
- Kyohei Nakamura
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Affiliation Department of Immunobiology, Institute of Development, Aging and Cancer, Tohoku University, Aoba-ku, Sendai, Miyagi, Japan
- Mizuho Ono
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Affiliation Department of Immunobiology, Institute of Development, Aging and Cancer, Tohoku University, Aoba-ku, Sendai, Miyagi, Japan
- Tadashi Nishiya
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Affiliation Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, Kita-ku, Okayama, Japan
- Syou Nakamura
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Affiliation Department of Immunobiology, Institute of Development, Aging and Cancer, Tohoku University, Aoba-ku, Sendai, Miyagi, Japan
- Yuri Takeda
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Affiliations Department of Immunobiology, Institute of Development, Aging and Cancer, Tohoku University, Aoba-ku, Sendai, Miyagi, Japan, Graduate School of Dentistry, Tohoku University, Aoba-ku, Sendai, Miyagi, Japan
- Akira Dobashi
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Affiliation Department of Immunobiology, Institute of Development, Aging and Cancer, Tohoku University, Aoba-ku, Sendai, Miyagi, Japan
- Akiko Takahashi
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Affiliation Department of Immunobiology, Institute of Development, Aging and Cancer, Tohoku University, Aoba-ku, Sendai, Miyagi, Japan
- Misato Endo
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Affiliation Department of Immunobiology, Institute of Development, Aging and Cancer, Tohoku University, Aoba-ku, Sendai, Miyagi, Japan
- Akiyo Ito
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Affiliation Department of Immunobiology, Institute of Development, Aging and Cancer, Tohoku University, Aoba-ku, Sendai, Miyagi, Japan
- Kyosuke Ueda
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Affiliation Department of Materials Processing, Graduate School of Engineering, Tohoku University, Aramakiaza, Aoba-ku, Sendai, Miyagi, Japan
- Naoki Sato
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Affiliation Department of Immunobiology, Institute of Development, Aging and Cancer, Tohoku University, Aoba-ku, Sendai, Miyagi, Japan
- Shigehito Higuchi
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Affiliation Department of Immunobiology, Institute of Development, Aging and Cancer, Tohoku University, Aoba-ku, Sendai, Miyagi, Japan
- Takeru Kondo
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Affiliation Department of Immunobiology, Institute of Development, Aging and Cancer, Tohoku University, Aoba-ku, Sendai, Miyagi, Japan
- Suguru Hashimoto
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Affiliation Department of Immunobiology, Institute of Development, Aging and Cancer, Tohoku University, Aoba-ku, Sendai, Miyagi, Japan
- Masamichi Watanabe
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Affiliation Department of Immunobiology, Institute of Development, Aging and Cancer, Tohoku University, Aoba-ku, Sendai, Miyagi, Japan
- Makoto Watanabe
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Affiliation Graduate School of Dentistry, Tohoku University, Aoba-ku, Sendai, Miyagi, Japan
- Tetsu Takahashi
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Affiliation Graduate School of Dentistry, Tohoku University, Aoba-ku, Sendai, Miyagi, Japan
- Keiichi Sasaki
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Affiliation Graduate School of Dentistry, Tohoku University, Aoba-ku, Sendai, Miyagi, Japan
- Masanori Nakamura
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Affiliation Graduate School of Dentistry, Showa University, Shinagawa-ku, Tokyo, Japan
- Takehiko Sasazuki
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Affiliation Institute for Advanced Study, Kyushu University, Higashi-ku, Fukuoka, Japan
- Takayuki Narushima
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Affiliation Department of Materials Processing, Graduate School of Engineering, Tohoku University, Aramakiaza, Aoba-ku, Sendai, Miyagi, Japan
- Ryuji Suzuki
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Affiliation Department of Rheumatology and Clinical Immunology, Clinical Research Center for Allergy and Rheumatology, Sagamihara National Hospital, National Hospital Organization, Minami-ku, Sagamihara, Kanagawa, Japan
- Kouetsu Ogasawara
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* E-mail: ogasawara@idac.tohoku.ac.jp
Affiliation Department of Immunobiology, Institute of Development, Aging and Cancer, Tohoku University, Aoba-ku, Sendai, Miyagi, Japan
Competing Interests
KO has licensed intellectual property rights relative to NKG2D for commercial applications (University of California, San Francisco). There are no further patents, products in development or marketed products to declare. This does not alter the authors' adherence to all the PLOS ONE policies on sharing data and materials, as detailed online in the guide for authors.
Author Contributions
Conceived and designed the experiments: KO MK. Performed the experiments: MK YA Masamichi Watanabe MO SN AD. Analyzed the data: KO MK M. Nakayama T. Nishiya KN Masamichi Watanabe KS M. Nakamura TS T. Narushima RS MO SN AD AT ME AI KU NS S. Hashimoto YT TT TK S. Higuchi Makoto Watanabe. Contributed reagents/materials/analysis tools: KO MK M. Nakayama YA. Wrote the manuscript: KO, MK, Masafumi Nakayama.